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Discovery of Potent and Selective Antibody-Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization.
Karpov AS, Nieto-Oberhuber CM, Abrams T, Beng-Louka E, Blanco E, Chamoin S, Chene P, Dacquignies I, Daniel D, Dillon MP, Doumampouom-Metoul L, Drosos N, Fedoseev P, Furegati M, Granda B, Grotzfeld RM, Hess Clark S, Joly E, Jones D, Lacaud-Baumlin M, Lagasse-Guerro S, Lorenzana EG, Mallet W, Martyniuk P, Marzinzik AL, Mesrouze Y, Nocito S, Oei Y, Perruccio F, Piizzi G, Richard E, Rudewicz PJ, Schindler P, Velay M, Venstrom K, Wang P, Zurini M, Lafrance M. Karpov AS, et al. Among authors: richard e. ACS Med Chem Lett. 2019 Dec 3;10(12):1674-1679. doi: 10.1021/acsmedchemlett.9b00468. eCollection 2019 Dec 12. ACS Med Chem Lett. 2019. PMID: 31857845 Free PMC article.
Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol.
Fu Y, Estoppey D, Roggo S, Pistorius D, Fuchs F, Studer C, Ibrahim AS, Aust T, Grandjean F, Mihalic M, Memmert K, Prindle V, Richard E, Riedl R, Schuierer S, Weber E, Hunziker J, Petersen F, Tao J, Hoepfner D. Fu Y, et al. Among authors: richard e. Nat Commun. 2020 Jul 7;11(1):3387. doi: 10.1038/s41467-020-17221-5. Nat Commun. 2020. PMID: 32636417 Free PMC article.
Promoter-Driven Overexpression in Chromobacterium vaccinii Facilitates Access to FR900359 and Yields Novel Low Abundance Analogs.
Pistorius D, Buntin K, Weber E, Richard E, Bouquet C, Wollbrett S, Regenass H, Peón V, Böhm M, Kessler R, Gempeler T, Haberkorn A, Wimmer L, Lanshoeft C, Davis J, Hainzl D, D'Alessio JA, Manchado E, Petersen F. Pistorius D, et al. Among authors: richard e. Chemistry. 2022 Feb 7;28(8):e202103888. doi: 10.1002/chem.202103888. Epub 2021 Dec 28. Chemistry. 2022. PMID: 34878202
Author Correction: Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol.
Fu Y, Estoppey D, Roggo S, Pistorius D, Fuchs F, Studer C, Ibrahim AS, Aust T, Grandjean F, Mihalic M, Memmert K, Prindle V, Richard E, Riedl R, Schuierer S, Weber E, Hunziker J, Petersen F, Tao J, Hoepfner D. Fu Y, et al. Among authors: richard e. Nat Commun. 2020 Jul 31;11(1):3913. doi: 10.1038/s41467-020-17748-7. Nat Commun. 2020. PMID: 32737318 Free PMC article.
Prevention of dementia using mobile phone applications (PRODEMOS): a multinational, randomised, controlled effectiveness-implementation trial.
van Charante EPM, Hoevenaar-Blom MP, Song M, Andrieu S, Barnes L, Birck C, Brooks R, Coley N, Eggink E, Georges J, Hafdi M, van Gool WA, Handels R, Hou H, Lyu J, Niu Y, Song L, Wang W, Wang Y, Wimo A, Yu Y, Zhang J, Zhang W, Brayne C, Wang W, Richard E; PRODEMOS study group. van Charante EPM, et al. Among authors: richard e. Lancet Healthy Longev. 2024 May 14:S2666-7568(24)00068-0. doi: 10.1016/S2666-7568(24)00068-0. Online ahead of print. Lancet Healthy Longev. 2024. PMID: 38763155 Free article.
Safety and efficacy of active blood-pressure reduction to the recommended thresholds for intravenous thrombolysis in patients with acute ischaemic stroke in the Netherlands (TRUTH): a prospective, observational, cluster-based, parallel-group study.
Zonneveld TP, Vermeer SE, van Zwet EW, Groot AED, Algra A, Aerden LAM, Alblas KCL, de Beer F, Brouwers PJAM, de Gans K, van Gemert HMA, van Ginneken BCAM, Grooters GS, Halkes PHA, van der Heijden-Montfroy TAMHG, Jellema K, de Jong SW, Lövenich-Ciccarello H, van der Meulen WDM, Peters EW, van der Ree TC, Remmers MJM, Richard E, Rovers JMP, Saxena R, van Schaik SM, Schonewille WJ, Schreuder TAHCML, de Schryver ELLM, Schuiling WJ, Spaander FH, van Tuijl JH, Visser MC, Zinkstok SM, Zock E, Dippel DWJ, Kappelle LJ, van Oostenbrugge RJ, Roos YBWEM, Vermeij FH, Wermer MJH, van der Worp HB, Nederkoorn PJ, Kruyt ND. Zonneveld TP, et al. Among authors: richard e. Lancet Neurol. 2024 May 15:S1474-4422(24)00177-7. doi: 10.1016/S1474-4422(24)00177-7. Online ahead of print. Lancet Neurol. 2024. PMID: 38763149
639 results