Rich JN - Search Results

1

High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor.

Lathia JD, Li M, Sinyuk M, Alvarado AG, Flavahan WA, Stoltz K, Rosager AM, Hale J, Hitomi M, Gallagher J, Wu Q, Martin J, Vidal JG, Nakano I, Dahlrot RH, Hansen S, McLendon RE, Sloan AE, Bao S, Hjelmeland AB, Carson CT, Naik UP, Kristensen B, Rich JN. Lathia JD, et al. Among authors: rich jn. Cell Rep. 2014 Jan 16;6(1):117-29. doi: 10.1016/j.celrep.2013.11.043. Epub 2013 Dec 27. Cell Rep. 2014. PMID: 24373972 Free PMC article.

2

A genetically tractable model of human glioma formation.

Rich JN, Guo C, McLendon RE, Bigner DD, Wang XF, Counter CM. Rich JN, et al. Cancer Res. 2001 May 1;61(9):3556-60. Cancer Res. 2001. PMID: 11325817

3

Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway.

Bao S, Ouyang G, Bai X, Huang Z, Ma C, Liu M, Shao R, Anderson RM, Rich JN, Wang XF. Bao S, et al. Among authors: rich jn. Cancer Cell. 2004 Apr;5(4):329-39. doi: 10.1016/s1535-6108(04)00081-9. Cancer Cell. 2004. PMID: 15093540 Free article.

4

SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility.

Hjelmeland MD, Hjelmeland AB, Sathornsumetee S, Reese ED, Herbstreith MH, Laping NJ, Friedman HS, Bigner DD, Wang XF, Rich JN. Hjelmeland MD, et al. Among authors: rich jn. Mol Cancer Ther. 2004 Jun;3(6):737-45. Mol Cancer Ther. 2004. PMID: 15210860

5

Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation.

Shi Q, Bao S, Maxwell JA, Reese ED, Friedman HS, Bigner DD, Wang XF, Rich JN. Shi Q, et al. Among authors: rich jn. J Biol Chem. 2004 Dec 10;279(50):52200-9. doi: 10.1074/jbc.M409630200. Epub 2004 Oct 5. J Biol Chem. 2004. PMID: 15469933 Free article.

6

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition.

Goudar RK, Shi Q, Hjelmeland MD, Keir ST, McLendon RE, Wikstrand CJ, Reese ED, Conrad CA, Traxler P, Lane HA, Reardon DA, Cavenee WK, Wang XF, Bigner DD, Friedman HS, Rich JN. Goudar RK, et al. Among authors: rich jn. Mol Cancer Ther. 2005 Jan;4(1):101-12. Mol Cancer Ther. 2005. PMID: 15657358

7

Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity.

Hjelmeland AB, Hjelmeland MD, Shi Q, Hart JL, Bigner DD, Wang XF, Kontos CD, Rich JN. Hjelmeland AB, et al. Among authors: rich jn. Cancer Res. 2005 Dec 15;65(24):11276-81. doi: 10.1158/0008-5472.CAN-05-3016. Cancer Res. 2005. PMID: 16357132

8

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor.

Bao S, Wu Q, Sathornsumetee S, Hao Y, Li Z, Hjelmeland AB, Shi Q, McLendon RE, Bigner DD, Rich JN. Bao S, et al. Among authors: rich jn. Cancer Res. 2006 Aug 15;66(16):7843-8. doi: 10.1158/0008-5472.CAN-06-1010. Cancer Res. 2006. PMID: 16912155

9

AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma.

Sathornsumetee S, Hjelmeland AB, Keir ST, McLendon RE, Batt D, Ramsey T, Yusuff N, Rasheed BK, Kieran MW, Laforme A, Bigner DD, Friedman HS, Rich JN. Sathornsumetee S, et al. Among authors: rich jn. Cancer Res. 2006 Sep 1;66(17):8722-30. doi: 10.1158/0008-5472.CAN-06-0284. Cancer Res. 2006. PMID: 16951188

10

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.

Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. Bao S, et al. Among authors: rich jn. Nature. 2006 Dec 7;444(7120):756-60. doi: 10.1038/nature05236. Epub 2006 Oct 18. Nature. 2006. PMID: 17051156

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