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Chemical and biological characterisation of Machaerium hirtum (Vell.) Stellfeld: absence of cytotoxicity and mutagenicity and possible chemopreventive potential.
Ribeiro DL, Cilião HL, Specian AF, Serpeloni JM, de Souza MF, Tangerina MM, Vilegas W, Boldrin PK, Resende FA, Varanda EA, Martínez-López W, Sannomiya M, Cólus IM. Ribeiro DL, et al. Mutagenesis. 2016 Mar;31(2):147-60. doi: 10.1093/mutage/gev066. Epub 2015 Aug 27. Mutagenesis. 2016. PMID: 26314304
LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds.
Specian AF, Serpeloni JM, Tuttis K, Ribeiro DL, Cilião HL, Varanda EA, Sannomiya M, Martinez-Lopez W, Vilegas W, Cólus IM. Specian AF, et al. Among authors: ribeiro dl. Cytotechnology. 2016 Dec;68(6):2729-2744. doi: 10.1007/s10616-016-9998-6. Epub 2016 Jun 25. Cytotechnology. 2016. PMID: 27344148 Free PMC article.
Phytochemical study and evaluation of cytotoxicity, mutagenicity, cell cycle kinetics and gene expression of Bauhinia holophylla (Bong.) Steud. in HepG2 cells in vitro.
Ribeiro DL, Cilião HL, Specian AFL, Serpeloni JM, De Oliveira MT, Varanda EA, Vilegas W, Saldanha LL, Martínez-López W, Dokkedal AL, Cólus IMS. Ribeiro DL, et al. Cytotechnology. 2018 Apr;70(2):713-728. doi: 10.1007/s10616-017-0173-5. Epub 2017 Dec 11. Cytotechnology. 2018. PMID: 29230630 Free PMC article.
Fridericia platyphylla (Cham.) L.G. Lohmann root extract exerts cytotoxic and antiproliferative effects on gastric tumor cells and downregulates BCL-XL, BIRC5, and MET genes.
Serpeloni JM, Specian A, Ribeiro DL, Benício LM, Nunes HL, Franchi LP, Rocha CQ, Vilegas W, Varanda EA, Cólus I. Serpeloni JM, et al. Among authors: ribeiro dl. Hum Exp Toxicol. 2020 Mar;39(3):338-354. doi: 10.1177/0960327119888261. Epub 2019 Nov 14. Hum Exp Toxicol. 2020. PMID: 31726875
Synephrine and caffeine combination promotes cytotoxicity, DNA damage and transcriptional modulation of apoptosis-related genes in human HepG2 cells.
Leão TK, Ribeiro DL, Machado ART, Costa TR, Sampaio SV, Antunes LMG. Leão TK, et al. Among authors: ribeiro dl. Mutat Res Genet Toxicol Environ Mutagen. 2021 Aug-Sep;868-869:503375. doi: 10.1016/j.mrgentox.2021.503375. Epub 2021 Jul 9. Mutat Res Genet Toxicol Environ Mutagen. 2021. PMID: 34454690 Free article.
88 results