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SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.
Lukinović V, Hausmann S, Roth GS, Oyeniran C, Ahmad T, Tsao N, Brickner JR, Casanova AG, Chuffart F, Benitez AM, Vayr J, Rodell R, Tardif M, Jansen PWTC, Couté Y, Vermeulen M, Hainaut P, Mazur PK, Mosammaparast N, Reynoird N. Lukinović V, et al. Among authors: reynoird n. Cancer Discov. 2022 Sep 2;12(9):2158-2179. doi: 10.1158/2159-8290.CD-21-0205. Cancer Discov. 2022. PMID: 35819319 Free PMC article.
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, Sage J, Gozani O. Mazur PK, et al. Among authors: reynoird n. Nature. 2014 Jun 12;510(7504):283-7. doi: 10.1038/nature13320. Epub 2014 May 21. Nature. 2014. PMID: 24847881 Free PMC article.
Lysine methylation signaling in pancreatic cancer.
Roth GS, Casanova AG, Lemonnier N, Reynoird N. Roth GS, et al. Among authors: reynoird n. Curr Opin Oncol. 2018 Jan;30(1):30-37. doi: 10.1097/CCO.0000000000000421. Curr Opin Oncol. 2018. PMID: 29076964
Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells.
Shiota H, Barral S, Buchou T, Tan M, Couté Y, Charbonnier G, Reynoird N, Boussouar F, Gérard M, Zhu M, Bargier L, Puthier D, Chuffart F, Bourova-Flin E, Picaud S, Filippakopoulos P, Goudarzi A, Ibrahim Z, Panne D, Rousseaux S, Zhao Y, Khochbin S. Shiota H, et al. Among authors: reynoird n. Cell Rep. 2018 Sep 25;24(13):3477-3487.e6. doi: 10.1016/j.celrep.2018.08.069. Cell Rep. 2018. PMID: 30257209 Free article.
Aberrant RNA methylation triggers recruitment of an alkylation repair complex.
Tsao N, Brickner JR, Rodell R, Ganguly A, Wood M, Oyeniran C, Ahmad T, Sun H, Bacolla A, Zhang L, Lukinović V, Soll JM, Townley BA, Casanova AG, Tainer JA, He C, Vindigni A, Reynoird N, Mosammaparast N. Tsao N, et al. Among authors: reynoird n. Mol Cell. 2021 Oct 21;81(20):4228-4242.e8. doi: 10.1016/j.molcel.2021.09.024. Mol Cell. 2021. PMID: 34686315 Free PMC article.
Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis.
Casanova AG, Roth GS, Hausmann S, Lu X, Belmudes L, Bourova-Flin E, Flores NM, Benitez AM, Caporicci M, Vayr J, Blanchet S, Ielasi F, Rousseaux S, Hainaut P, Gozani O, Couté Y, Palencia A, Mazur PK, Reynoird N. Casanova AG, et al. Among authors: reynoird n. bioRxiv [Preprint]. 2023 Sep 18:2023.09.18.558201. doi: 10.1101/2023.09.18.558201. bioRxiv. 2023. PMID: 37790557 Free PMC article. Updated. Preprint.
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