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Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.
Rodríguez-Lavado J, Gallardo-Garrido C, Mallea M, Bustos V, Osorio R, Hödar-Salazar M, Chung H, Araya-Maturana R, Lorca M, Pessoa-Mahana CD, Mella-Raipán J, Saitz C, Jaque P, Reyes-Parada M, Iturriaga-Vásquez P, Pessoa-Mahana H. Rodríguez-Lavado J, et al. Eur J Med Chem. 2020 Jul 15;198:112368. doi: 10.1016/j.ejmech.2020.112368. Epub 2020 Apr 29. Eur J Med Chem. 2020. PMID: 32388114
Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor.
Pessoa-Mahana H, González-Lira C, Fierro A, Zapata-Torres G, Pessoa-Mahana CD, Ortiz-Severin J, Iturriaga-Vásquez P, Reyes-Parada M, Silva-Matus P, Saitz-Barría C, Araya-Maturana R. Pessoa-Mahana H, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7604-11. doi: 10.1016/j.bmc.2013.10.036. Epub 2013 Nov 6. Bioorg Med Chem. 2013. PMID: 24262884
Synthesis and Docking of Novel 3-Indolylpropyl Derivatives as New Polypharmacological Agents Displaying Affinity for 5-HT1A R/SERT.
Pessoa-Mahana H, Silva-Matus P, Pessoa-Mahana CD, Chung H, Iturriaga-Vásquez P, Quiroz G, Möller-Acuña P, Zapata-Torres G, Saitz-Barría C, Araya-Maturana R, Reyes-Parada M. Pessoa-Mahana H, et al. Arch Pharm (Weinheim). 2017 Jan;350(1). doi: 10.1002/ardp.201600271. Epub 2016 Dec 16. Arch Pharm (Weinheim). 2017. PMID: 27981607
Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands.
Cerda-Cavieres C, Quiroz G, Iturriaga-Vásquez P, Rodríguez-Lavado J, Alarcón-Espósito J, Saitz C, Pessoa-Mahana CD, Chung H, Araya-Maturana R, Mella-Raipán J, Cabezas D, Ojeda-Gómez C, Reyes-Parada M, Pessoa-Mahana H. Cerda-Cavieres C, et al. Among authors: reyes parada m. Molecules. 2020 Oct 10;25(20):4614. doi: 10.3390/molecules25204614. Molecules. 2020. PMID: 33050524 Free PMC article.
Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters.
González-Gutiérrez JP, Pessoa-Mahana HA, Iturriaga-Vásquez PE, Reyes-Parada MI, Guerra-Díaz NE, Hodar-Salazar M, Viscarra F, Paillali P, Núñez-Vivanco G, Lorca-Carvajal MA, Mella-Raipán J, Zúñiga MC. González-Gutiérrez JP, et al. Molecules. 2019 Oct 22;24(20):3808. doi: 10.3390/molecules24203808. Molecules. 2019. PMID: 31652614 Free PMC article.
Amphetamine Derivatives as Monoamine Oxidase Inhibitors.
Reyes-Parada M, Iturriaga-Vasquez P, Cassels BK. Reyes-Parada M, et al. Front Pharmacol. 2020 Jan 23;10:1590. doi: 10.3389/fphar.2019.01590. eCollection 2019. Front Pharmacol. 2020. PMID: 32038257 Free PMC article. Review.
58 results