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The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models.
Sousa JC, Milner E, Carroll D, McCalmont W, Gardner S, Moon J, Johnson JD, Lee P, Auschwitz J, Roncal N, Caridha D, Tungteung A, Zeng Q, Reyes S, Smith B, Li Q, Kozar MP, Melendez V, Dow G. Sousa JC, et al. Among authors: reyes s. Eur J Drug Metab Pharmacokinet. 2014 Dec;39(4):231-6. doi: 10.1007/s13318-013-0162-9. Epub 2014 Apr 7. Eur J Drug Metab Pharmacokinet. 2014. PMID: 24705994
Supramolecular citrate poly allylamine hydrochloride nanoparticles for citrate delivery and calcium oxalate nanocrystal dissolution.
Gianvincenzo PD, Leyes MF, Boonkam K, Puentes AF, Reyes SG, Nardi AN, Olivieri A, Pummarin S, Kamonsutthipaijit N, Amenitsch H, Ritacco H, D'Abramo M, Ortore MG, Boonla C, Moya SE. Gianvincenzo PD, et al. Among authors: reyes sg. J Colloid Interface Sci. 2024 Apr 30;669:667-678. doi: 10.1016/j.jcis.2024.04.185. Online ahead of print. J Colloid Interface Sci. 2024. PMID: 38733878
Multivariate data analysis of process parameters affecting the growth and productivity of stable Chinese hamster ovary cell pools expressing SARS-CoV-2 spike protein as vaccine antigen in early process development.
Reyes SJ, Lemire L, Molina RS, Roy M, L'Ecuyer-Coelho H, Martynova Y, Cass B, Voyer R, Durocher Y, Henry O, Pham PL. Reyes SJ, et al. Biotechnol Prog. 2024 Apr 25:e3467. doi: 10.1002/btpr.3467. Online ahead of print. Biotechnol Prog. 2024. PMID: 38660973
Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study.
Schlapbach LJ, Ganesamoorthy D, Wilson C, Raman S, George S, Snelling PJ, Phillips N, Irwin A, Sharp N, Le Marsney R, Chavan A, Hempenstall A, Bialasiewicz S, MacDonald AD, Grimwood K, Kling JC, McPherson SJ, Blumenthal A, Kaforou M, Levin M, Herberg JA, Gibbons KS, Coin LJM; EUCLIDS consortium; RAPIDS Study Group. Schlapbach LJ, et al. Lancet Child Adolesc Health. 2024 May;8(5):325-338. doi: 10.1016/S2352-4642(24)00017-8. Epub 2024 Mar 19. Lancet Child Adolesc Health. 2024. PMID: 38513681
559 results