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Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging.
Sola-García A, Cáliz-Molina MÁ, Espadas I, Petr M, Panadero-Morón C, González-Morán D, Martín-Vázquez ME, Narbona-Pérez ÁJ, López-Noriega L, Martínez-Corrales G, López-Fernández-Sobrino R, Carmona-Marin LM, Martínez-Force E, Yanes O, Vinaixa M, López-López D, Reyes JC, Dopazo J, Martín F, Gauthier BR, Scheibye-Knudsen M, Capilla-González V, Martín-Montalvo A. Sola-García A, et al. Among authors: reyes jc. Commun Biol. 2023 Mar 8;6(1):250. doi: 10.1038/s42003-023-04625-4. Commun Biol. 2023. PMID: 36890357 Free PMC article.
The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.
Mellado-Gil JM, Fuente-Martín E, Lorenzo PI, Cobo-Vuilleumier N, López-Noriega L, Martín-Montalvo A, Gómez IGH, Ceballos-Chávez M, Gómez-Jaramillo L, Campos-Caro A, Romero-Zerbo SY, Rodríguez-Comas J, Servitja JM, Rojo-Martinez G, Hmadcha A, Soria B, Bugliani M, Marchetti P, Bérmudez-Silva FJ, Reyes JC, Aguilar-Diosdado M, Gauthier BR. Mellado-Gil JM, et al. Among authors: reyes jc. Cell Death Dis. 2018 Feb 15;9(3):279. doi: 10.1038/s41419-018-0272-z. Cell Death Dis. 2018. PMID: 29449530 Free PMC article.
Dissecting the Brain/Islet Axis in Metabesity.
Fuente-Martín E, Mellado-Gil JM, Cobo-Vuilleumier N, Martín-Montalvo A, Romero-Zerbo SY, Diaz Contreras I, Hmadcha A, Soria B, Martin Bermudo F, Reyes JC, Bermúdez-Silva FJ, Lorenzo PI, Gauthier BR. Fuente-Martín E, et al. Among authors: reyes jc. Genes (Basel). 2019 May 8;10(5):350. doi: 10.3390/genes10050350. Genes (Basel). 2019. PMID: 31072002 Free PMC article. Review.
The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity.
Lorenzo PI, Martin Vazquez E, López-Noriega L, Fuente-Martín E, Mellado-Gil JM, Franco JM, Cobo-Vuilleumier N, Guerrero Martínez JA, Romero-Zerbo SY, Perez-Cabello JA, Rivero Canalejo S, Campos-Caro A, Lachaud CC, Crespo Barreda A, Aguilar-Diosdado M, García Fuentes E, Martin-Montalvo A, Álvarez Dolado M, Martin F, Rojo-Martinez G, Pozo D, Bérmudez-Silva FJ, Comaills V, Reyes JC, Gauthier BR. Lorenzo PI, et al. Among authors: reyes jc. Theranostics. 2021 May 12;11(14):6983-7004. doi: 10.7150/thno.57237. eCollection 2021. Theranostics. 2021. PMID: 34093866 Free PMC article.
Histone availability as a strategy to control gene expression.
Prado F, Jimeno-González S, Reyes JC. Prado F, et al. Among authors: reyes jc. RNA Biol. 2017 Mar 4;14(3):281-286. doi: 10.1080/15476286.2016.1189071. Epub 2016 May 21. RNA Biol. 2017. PMID: 27211514 Free PMC article. Review.
Human prefoldin modulates co-transcriptional pre-mRNA splicing.
Payán-Bravo L, Fontalva S, Peñate X, Cases I, Guerrero-Martínez JA, Pareja-Sánchez Y, Odriozola-Gil Y, Lara E, Jimeno-González S, Suñé C, Muñoz-Centeno MC, Reyes JC, Chávez S. Payán-Bravo L, et al. Among authors: reyes jc. Nucleic Acids Res. 2021 Jun 21;49(11):6267-6280. doi: 10.1093/nar/gkab446. Nucleic Acids Res. 2021. PMID: 34096575 Free PMC article.
170 results