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Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion.
Wang X, Istvanffy R, Ye L, Teller S, Laschinger M, Diakopoulos KN, Görgülü K, Li Q, Ren L, Jäger C, Steiger K, Muckenhuber A, Vilne B, Çifcibaşı K, Reyes CM, Yurteri Ü, Kießler M, Gürçınar IH, Sugden M, Yıldızhan SE, Sezerman OU, Çilingir S, Süyen G, Reichert M, Schmid RM, Bärthel S, Oellinger R, Krüger A, Rad R, Saur D, Algül H, Friess H, Lesina M, Ceyhan GO, Demir IE. Wang X, et al. Among authors: reyes cm. J Clin Invest. 2023 Nov 1;133(21):e166333. doi: 10.1172/JCI166333. J Clin Invest. 2023. PMID: 37607005 Free PMC article.
Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells.
Demir IE, Kujundzic K, Pfitzinger PL, Saricaoglu ÖC, Teller S, Kehl T, Reyes CM, Ertl LS, Miao Z, Schall TJ, Tieftrunk E, Haller B, Diakopoulos KN, Kurkowski MU, Lesina M, Krüger A, Algül H, Friess H, Ceyhan GO. Demir IE, et al. Among authors: reyes cm. Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E85-E94. doi: 10.1073/pnas.1606909114. Epub 2016 Dec 16. Proc Natl Acad Sci U S A. 2017. PMID: 27986950 Free PMC article.
Clinically Actionable Strategies for Studying Neural Influences in Cancer.
Demir IE, Reyes CM, Alrawashdeh W, Ceyhan GO, Deborde S, Friess H, Görgülü K, Istvanffy R, Jungwirth D, Kuner R, Maryanovich M, Na'ara S, Renders S, Saloman JL, Scheff NN, Steenfadt H, Stupakov P, Thiel V, Verma D, Yilmaz BS, White RA, Wang TC, Wong RJ, Frenette PS, Gil Z, Davis BM. Demir IE, et al. Among authors: reyes cm. Cancer Cell. 2020 Jul 13;38(1):11-14. doi: 10.1016/j.ccell.2020.05.023. Epub 2020 Jun 11. Cancer Cell. 2020. PMID: 32531270 Free article.
Neoadjuvant chemotherapy is associated with suppression of the B cell-centered immune landscape in pancreatic ductal adenocarcinoma.
Rupp L, Dietsche I, Kießler M, Sommer U, Muckenhuber A, Steiger K, van Eijck CWF, Richter L, Istvanffy R, Jäger C, Friess H, van Eijck CHJ, Demir IE, Reyes CM, Schmitz M. Rupp L, et al. Among authors: reyes cm. Front Immunol. 2024 Apr 2;15:1378190. doi: 10.3389/fimmu.2024.1378190. eCollection 2024. Front Immunol. 2024. PMID: 38629072 Free PMC article.
Assessment of symptoms in COMET-ICE, a phase 2/3 study of sotrovimab for early treatment of non-hospitalized patients with COVID-19.
Satram S, Ghafoori P, Reyes CM, Keeley TJH, Birch HJ, Brintziki D, Aldinger M, Alexander E, Lopuski A, Sarkis EH, Gupta A, Shapiro AE, Powers JH 3rd. Satram S, et al. Among authors: reyes cm. J Patient Rep Outcomes. 2023 Sep 13;7(1):92. doi: 10.1186/s41687-023-00621-8. J Patient Rep Outcomes. 2023. PMID: 37702920 Free PMC article. Clinical Trial.
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