Reszka AP - Search Results

1

Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries.

Rahman KM, Tizkova K, Reszka AP, Neidle S, Thurston DE. Rahman KM, et al. Among authors: reszka ap. Bioorg Med Chem Lett. 2012 Apr 15;22(8):3006-10. doi: 10.1016/j.bmcl.2012.02.020. Epub 2012 Feb 16. Bioorg Med Chem Lett. 2012. PMID: 22421021

2

Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents.

Martins C, Gunaratnam M, Stuart J, Makwana V, Greciano O, Reszka AP, Kelland LR, Neidle S. Martins C, et al. Among authors: reszka ap. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2293-8. doi: 10.1016/j.bmcl.2007.01.056. Epub 2007 Jan 25. Bioorg Med Chem Lett. 2007. PMID: 17276687

3

Targeting pancreatic cancer with a G-quadruplex ligand.

Gunaratnam M, de la Fuente M, Hampel SM, Todd AK, Reszka AP, Schätzlein A, Neidle S. Gunaratnam M, et al. Among authors: reszka ap. Bioorg Med Chem. 2011 Dec 1;19(23):7151-7. doi: 10.1016/j.bmc.2011.09.055. Epub 2011 Oct 10. Bioorg Med Chem. 2011. PMID: 22041170

4

Sequences in the HSP90 promoter form G-quadruplex structures with selectivity for disubstituted phenyl bis-oxazole derivatives.

Ohnmacht SA, Micco M, Petrucci V, Todd AK, Reszka AP, Gunaratnam M, Carvalho MA, Zloh M, Neidle S. Ohnmacht SA, et al. Among authors: reszka ap. Bioorg Med Chem Lett. 2012 Sep 15;22(18):5930-5. doi: 10.1016/j.bmcl.2012.07.065. Epub 2012 Jul 23. Bioorg Med Chem Lett. 2012. PMID: 22892119

5

Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.

Harrison RJ, Cuesta J, Chessari G, Read MA, Basra SK, Reszka AP, Morrell J, Gowan SM, Incles CM, Tanious FA, Wilson WD, Kelland LR, Neidle S. Harrison RJ, et al. Among authors: reszka ap. J Med Chem. 2003 Oct 9;46(21):4463-76. doi: 10.1021/jm0308693. J Med Chem. 2003. PMID: 14521409

6

Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding.

Harrison RJ, Reszka AP, Haider SM, Romagnoli B, Morrell J, Read MA, Gowan SM, Incles CM, Kelland LR, Neidle S. Harrison RJ, et al. Among authors: reszka ap. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5845-9. doi: 10.1016/j.bmcl.2004.09.037. Bioorg Med Chem Lett. 2004. PMID: 15501053

7

Structural basis of DNA quadruplex recognition by an acridine drug.

Campbell NH, Parkinson GN, Reszka AP, Neidle S. Campbell NH, et al. Among authors: reszka ap. J Am Chem Soc. 2008 May 28;130(21):6722-4. doi: 10.1021/ja8016973. Epub 2008 May 6. J Am Chem Soc. 2008. PMID: 18457389

8

Rational design of substituted diarylureas: a scaffold for binding to G-quadruplex motifs.

Drewe WC, Nanjunda R, Gunaratnam M, Beltran M, Parkinson GN, Reszka AP, Wilson WD, Neidle S. Drewe WC, et al. Among authors: reszka ap. J Med Chem. 2008 Dec 25;51(24):7751-67. doi: 10.1021/jm801245v. J Med Chem. 2008. PMID: 19053833 Free PMC article.

9

Targeting human gastrointestinal stromal tumor cells with a quadruplex-binding small molecule.

Gunaratnam M, Swank S, Haider SM, Galesa K, Reszka AP, Beltran M, Cuenca F, Fletcher JA, Neidle S. Gunaratnam M, et al. Among authors: reszka ap. J Med Chem. 2009 Jun 25;52(12):3774-83. doi: 10.1021/jm900424a. J Med Chem. 2009. PMID: 19469547 Free PMC article.

10

Biaryl polyamides as a new class of DNA quadruplex-binding ligands.

Rahman KM, Reszka AP, Gunaratnam M, Haider SM, Howard PW, Fox KR, Neidle S, Thurston DE. Rahman KM, et al. Among authors: reszka ap. Chem Commun (Camb). 2009 Jul 21;(27):4097-9. doi: 10.1039/b902359c. Epub 2009 Jun 5. Chem Commun (Camb). 2009. PMID: 19568645

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