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Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5.
Hartmann J, Bajaj T, Klengel C, Chatzinakos C, Ebert T, Dedic N, McCullough KM, Lardenoije R, Joëls M, Meijer OC, McCann KE, Dudek SM, Sarabdjitsingh RA, Daskalakis NP, Klengel T, Gassen NC, Schmidt MV, Ressler KJ. Hartmann J, et al. Among authors: ressler kj. Cell Rep. 2021 Jun 1;35(9):109185. doi: 10.1016/j.celrep.2021.109185. Cell Rep. 2021. PMID: 34077736 Free PMC article.
Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies.
Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J, Mercer KB, Pütz B, Bradley B, Holsboer F, Ressler KJ, Müller-Myhsok B, Binder EB. Mehta D, et al. Among authors: ressler kj. Arch Gen Psychiatry. 2011 Sep;68(9):901-10. doi: 10.1001/archgenpsychiatry.2011.50. Epub 2011 May 2. Arch Gen Psychiatry. 2011. PMID: 21536970 Free PMC article.
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions.
Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Pace TW, Mercer KB, Mayberg HS, Bradley B, Nemeroff CB, Holsboer F, Heim CM, Ressler KJ, Rein T, Binder EB. Klengel T, et al. Among authors: ressler kj. Nat Neurosci. 2013 Jan;16(1):33-41. doi: 10.1038/nn.3275. Epub 2012 Dec 2. Nat Neurosci. 2013. PMID: 23201972 Free PMC article.
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder.
Mehta D, Klengel T, Conneely KN, Smith AK, Altmann A, Pace TW, Rex-Haffner M, Loeschner A, Gonik M, Mercer KB, Bradley B, Müller-Myhsok B, Ressler KJ, Binder EB. Mehta D, et al. Among authors: ressler kj. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8302-7. doi: 10.1073/pnas.1217750110. Epub 2013 Apr 29. Proc Natl Acad Sci U S A. 2013. PMID: 23630272 Free PMC article.
DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.
Wingo AP, Almli LM, Stevens JS, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, Bradley B, Binder EB, Jin P, Gibson G, Ressler KJ. Wingo AP, et al. Among authors: ressler kj. Nat Commun. 2015 Dec 3;6:10106. doi: 10.1038/ncomms10106. Nat Commun. 2015. PMID: 26632874 Free PMC article.
LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family.
Guffanti G, Gaudi S, Klengel T, Fallon JH, Mangalam H, Madduri R, Rodriguez A, DeCrescenzo P, Glovienka E, Sobell J, Klengel C, Pato M, Ressler KJ, Pato C, Macciardi F. Guffanti G, et al. Among authors: ressler kj. Am J Med Genet B Neuropsychiatr Genet. 2016 Jun;171(4):534-45. doi: 10.1002/ajmg.b.32437. Epub 2016 Mar 16. Am J Med Genet B Neuropsychiatr Genet. 2016. PMID: 26990047
499 results