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Endothelial Progenitor Cells Promote Osteosarcoma Progression and Invasiveness via AKT/PI3K Signaling.
Doppelt-Flikshtain O, Younis A, Tamari T, Ginesin O, Shentzer-Kutiel T, Nikomarov D, Bar-Sela G, Coyac BR, Assaraf YG, Zigdon-Giladi H. Doppelt-Flikshtain O, et al. Cancers (Basel). 2023 Mar 17;15(6):1818. doi: 10.3390/cancers15061818. Cancers (Basel). 2023. PMID: 36980704 Free PMC article.
Endothelial progenitor cells (EPCs) mediate the angiogenic switch in several cancers. The spatial proximity between EPCs and OS in the bone led to the hypothesis that EPCs-osteosarcoma interactions may possibly promote OS progression and aggressiveness. ...
Endothelial progenitor cells (EPCs) mediate the angiogenic switch in several cancers. The spatial proximity between EPCs and OS in the bo …
Use of transforming growth factor-beta loaded onto beta-tricalcium phosphate scaffold in a bone regeneration rat calvaria model.
Elimelech R, Khoury N, Tamari T, Blumenfeld I, Gutmacher Z, Zigdon-Giladi H. Elimelech R, et al. Clin Implant Dent Relat Res. 2019 Aug;21(4):593-601. doi: 10.1111/cid.12775. Epub 2019 Apr 26. Clin Implant Dent Relat Res. 2019. PMID: 31025823
A positive effect on MSCs osteogenic differentiation was found.Bone height and bone area fraction in vivo were similar with or without TGF-beta(1) ; however, blood vessel density and degradation of the scaffold were significantly higher in the TGF-beta(1) group. CON …
A positive effect on MSCs osteogenic differentiation was found.Bone height and bone area fraction in vivo were similar with or …