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Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype.
Bavo F, Pallavicini M, Gotti C, Appiani R, Moretti M, Colombo SF, Pucci S, Viani P, Budriesi R, Renzi M, Fucile S, Bolchi C. Bavo F, et al. Among authors: renzi m. J Med Chem. 2020 Dec 24;63(24):15668-15692. doi: 10.1021/acs.jmedchem.0c01150. Epub 2020 Dec 16. J Med Chem. 2020. PMID: 33325696 Free article.
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9-nicotinic ligands on glioblastoma cells.
Pucci S, Bolchi C, Bavo F, Pallavicini M, De Palma C, Renzi M, Fucile S, Benfante R, Di Lascio S, Lattuada D, Bessereau JL, D'Alessandro M, Risson V, Zoli M, Clementi F, Gotti C. Pucci S, et al. Among authors: renzi m. Pharmacol Res. 2022 Jan;175:105959. doi: 10.1016/j.phrs.2021.105959. Epub 2021 Oct 28. Pharmacol Res. 2022. PMID: 34756924 Free article.
Microglia control glutamatergic synapses in the adult mouse hippocampus.
Basilico B, Ferrucci L, Ratano P, Golia MT, Grimaldi A, Rosito M, Ferretti V, Reverte I, Sanchini C, Marrone MC, Giubettini M, De Turris V, Salerno D, Garofalo S, St-Pierre MK, Carrier M, Renzi M, Pagani F, Modi B, Raspa M, Scavizzi F, Gross CT, Marinelli S, Tremblay MÈ, Caprioli D, Maggi L, Limatola C, Di Angelantonio S, Ragozzino D. Basilico B, et al. Among authors: renzi m. Glia. 2022 Jan;70(1):173-195. doi: 10.1002/glia.24101. Epub 2021 Oct 18. Glia. 2022. PMID: 34661306 Free PMC article.
Resilience to anhedonia-passive coping induced by early life experience is linked to a long-lasting reduction of Ih current in VTA dopaminergic neurons.
D'Addario SL, Di Segni M, Ledonne A, Piscitelli R, Babicola L, Martini A, Spoleti E, Mancini C, Ielpo D, D'Amato FR, Andolina D, Ragozzino D, Mercuri NB, Cifani C, Renzi M, Guatteo E, Ventura R. D'Addario SL, et al. Among authors: renzi m. Neurobiol Stress. 2021 Apr 15;14:100324. doi: 10.1016/j.ynstr.2021.100324. eCollection 2021 May. Neurobiol Stress. 2021. PMID: 33937445 Free PMC article.
233 results