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Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine.
Wu F, Li X, Looso M, Liu H, Ding D, Günther S, Kuenne C, Liu S, Weissmann N, Boettger T, Atzberger A, Kolahian S, Renz H, Offermanns S, Gärtner U, Potente M, Zhou Y, Yuan X, Braun T. Wu F, et al. Among authors: renz h. Nat Genet. 2023 Jan;55(1):100-111. doi: 10.1038/s41588-022-01252-3. Epub 2022 Dec 20. Nat Genet. 2023. PMID: 36539616 Free PMC article.
Vitamin D constrains inflammation by modulating the expression of key genes on Chr17q12-21.1.
Kilic A, Halu A, De Marzio M, Maiorino E, Duvall MG, Bruggemann TR, Rojas Quintero JJ, Chase R, Mirzakhani H, Sungur AÖ, Koepke J, Nakano T, Peh HY, Krishnamoorthy N, Abdulnour RE, Georgopoulos K, Litonjua AA, Demay M, Renz H, Levy BD, Weiss ST. Kilic A, et al. Among authors: renz h. Elife. 2024 Apr 3;12:RP89270. doi: 10.7554/eLife.89270. Elife. 2024. PMID: 38567749 Free PMC article.
Serum proteomics hint at an early T-cell response and modulation of SARS-CoV-2-related pathogenic pathways in COVID-19-ARDS treated with Ruxolitinib.
Völkel S, Tarawneh TS, Sacher L, Bhagwat AM, Karim I, Mack HID, Wiesmann T, Beutel B, Hoyer J, Keller C, Renz H, Burchert A, Neubauer A, Graumann J, Skevaki C, Mack EKM. Völkel S, et al. Among authors: renz h. Front Med (Lausanne). 2023 May 24;10:1176427. doi: 10.3389/fmed.2023.1176427. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37293294 Free PMC article.
From big data to better patient outcomes.
Hulsen T, Friedecký D, Renz H, Melis E, Vermeersch P, Fernandez-Calle P. Hulsen T, et al. Among authors: renz h. Clin Chem Lab Med. 2022 Dec 22;61(4):580-586. doi: 10.1515/cclm-2022-1096. Print 2023 Mar 28. Clin Chem Lab Med. 2022. PMID: 36539928 Free article.
Autoantibodies are highly prevalent in non-SARS-CoV-2 respiratory infections and critical illness.
Feng A, Yang EY, Moore AR, Dhingra S, Chang SE, Yin X, Pi R, Mack EK, Völkel S, Geßner R, Gündisch M, Neubauer A, Renz H, Tsiodras S, Fragkou PC, Asuni AA, Levitt JE, Wilson JG, Leong M, Lumb JH, Mao R, Pinedo K, Roque J, Richards CM, Stabile M, Swaminathan G, Salagianni ML, Triantafyllia V, Bertrams W, Blish CA, Carette JE, Frankovich J, Meffre E, Nadeau KC, Singh U, Wang TT, Luning Prak ET, Herold S, Andreakos E, Schmeck B, Skevaki C, Rogers AJ, Utz PJ. Feng A, et al. Among authors: renz h. JCI Insight. 2023 Feb 8;8(3):e163150. doi: 10.1172/jci.insight.163150. JCI Insight. 2023. PMID: 36752204 Free PMC article.
Validation of the Asthma Severity Scoring System (ASSESS) in the ALLIANCE Cohort.
Grychtol R, Riemann L, Gaedcke S, Liu B, DeLuca D, Förster R, Maison N, Thiele D, Jakobs N, Bahmer T, Meyer M, Foth S, Weber S, Rietschel E, Rabe KF, Kopp MV, von Mutius E, Dittrich AM, Hansen G; ALLIANCE Study Group as part of the German Center for Lung Research (DZL). Grychtol R, et al. J Allergy Clin Immunol. 2023 Jun;151(6):1525-1535.e4. doi: 10.1016/j.jaci.2023.01.027. Epub 2023 Feb 15. J Allergy Clin Immunol. 2023. PMID: 36804993 Free article.
576 results