Rennie PS - Search Results

1

Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors.

Radaeva M, Li H, LeBlanc E, Dalal K, Ban F, Ciesielski F, Chow B, Morin H, Awrey S, Singh K, Rennie PS, Lallous N, Cherkasov A. Radaeva M, et al. Among authors: rennie ps. Cells. 2022 Sep 7;11(18):2785. doi: 10.3390/cells11182785. Cells. 2022. PMID: 36139361 Free PMC article.

2

Androgen receptor plasticity and its implications for prostate cancer therapy.

Snow O, Lallous N, Singh K, Lack N, Rennie P, Cherkasov A. Snow O, et al. Cancer Treat Rev. 2019 Dec;81:101871. doi: 10.1016/j.ctrv.2019.05.001. Epub 2019 Jun 11. Cancer Treat Rev. 2019. PMID: 31698174 Review.

3

Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening.

Axerio-Cilies P, Lack NA, Nayana MR, Chan KH, Yeung A, Leblanc E, Guns ES, Rennie PS, Cherkasov A. Axerio-Cilies P, et al. Among authors: rennie ps. J Med Chem. 2011 Sep 22;54(18):6197-205. doi: 10.1021/jm200532b. Epub 2011 Aug 29. J Med Chem. 2011. PMID: 21846139

4

Identification of novel androgen receptor antagonists using structure- and ligand-based methods.

Li H, Ren X, Leblanc E, Frewin K, Rennie PS, Cherkasov A. Li H, et al. Among authors: rennie ps. J Chem Inf Model. 2013 Jan 28;53(1):123-30. doi: 10.1021/ci300514v. Epub 2013 Jan 16. J Chem Inf Model. 2013. PMID: 23278403

5

Targeting the binding function 3 (BF3) site of the androgen receptor through virtual screening. 2. development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole derivatives.

Munuganti RS, Leblanc E, Axerio-Cilies P, Labriere C, Frewin K, Singh K, Hassona MD, Lack NA, Li H, Ban F, Tomlinson Guns E, Young R, Rennie PS, Cherkasov A. Munuganti RS, et al. Among authors: rennie ps. J Med Chem. 2013 Feb 14;56(3):1136-48. doi: 10.1021/jm3015712. Epub 2013 Jan 18. J Med Chem. 2013. PMID: 23301637

6

Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer.

Lallous N, Dalal K, Cherkasov A, Rennie PS. Lallous N, et al. Among authors: rennie ps. Int J Mol Sci. 2013 Jun 14;14(6):12496-519. doi: 10.3390/ijms140612496. Int J Mol Sci. 2013. PMID: 23771019 Free PMC article. Review.

7

Discovery of 1H-indole-2-carboxamides as novel inhibitors of the androgen receptor binding function 3 (BF3).

Ban F, Leblanc E, Li H, Munuganti RS, Frewin K, Rennie PS, Cherkasov A. Ban F, et al. Among authors: rennie ps. J Med Chem. 2014 Aug 14;57(15):6867-72. doi: 10.1021/jm500684r. Epub 2014 Jul 25. J Med Chem. 2014. PMID: 25025737

8

Discovery of small-molecule inhibitors selectively targeting the DNA-binding domain of the human androgen receptor.

Li H, Ban F, Dalal K, Leblanc E, Frewin K, Ma D, Adomat H, Rennie PS, Cherkasov A. Li H, et al. Among authors: rennie ps. J Med Chem. 2014 Aug 14;57(15):6458-67. doi: 10.1021/jm500802j. Epub 2014 Aug 4. J Med Chem. 2014. PMID: 25062331

9

Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.

Dalal K, Roshan-Moniri M, Sharma A, Li H, Ban F, Hessein M, Hsing M, Singh K, LeBlanc E, Dehm S, Tomlinson Guns ES, Cherkasov A, Rennie PS. Dalal K, et al. Among authors: rennie ps. J Biol Chem. 2014 Sep 19;289(38):26417-26429. doi: 10.1074/jbc.M114.553818. Epub 2014 Aug 1. J Biol Chem. 2014. PMID: 25086042 Free PMC article.

10

Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients.

Lallous N, Volik SV, Awrey S, Leblanc E, Tse R, Murillo J, Singh K, Azad AA, Wyatt AW, LeBihan S, Chi KN, Gleave ME, Rennie PS, Collins CC, Cherkasov A. Lallous N, et al. Among authors: rennie ps. Genome Biol. 2016 Jan 26;17:10. doi: 10.1186/s13059-015-0864-1. Genome Biol. 2016. PMID: 26813233 Free PMC article.

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