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Total synthesis of chondramide C and its binding mode to F-actin.
Waldmann H, Hu TS, Renner S, Menninger S, Tannert R, Oda T, Arndt HD. Waldmann H, et al. Among authors: renner s. Angew Chem Int Ed Engl. 2008;47(34):6473-7. doi: 10.1002/anie.200801010. Angew Chem Int Ed Engl. 2008. PMID: 18624308 No abstract available.
A scaffold-tree-merging strategy for prospective bioactivity annotation of gamma-pyrones.
Wetzel S, Wilk W, Chammaa S, Sperl B, Roth AG, Yektaoglu A, Renner S, Berg T, Arenz C, Giannis A, Oprea TI, Rauh D, Kaiser M, Waldmann H. Wetzel S, et al. Among authors: renner s. Angew Chem Int Ed Engl. 2010 May 10;49(21):3666-70. doi: 10.1002/anie.200906555. Angew Chem Int Ed Engl. 2010. PMID: 20394088 No abstract available.
Small-molecule inhibition of APT1 affects Ras localization and signaling.
Dekker FJ, Rocks O, Vartak N, Menninger S, Hedberg C, Balamurugan R, Wetzel S, Renner S, Gerauer M, Schölermann B, Rusch M, Kramer JW, Rauh D, Coates GW, Brunsveld L, Bastiaens PI, Waldmann H. Dekker FJ, et al. Among authors: renner s. Nat Chem Biol. 2010 Jun;6(6):449-56. doi: 10.1038/nchembio.362. Epub 2010 Apr 25. Nat Chem Biol. 2010. PMID: 20418879
Interactive exploration of chemical space with Scaffold Hunter.
Wetzel S, Klein K, Renner S, Rauh D, Oprea TI, Mutzel P, Waldmann H. Wetzel S, et al. Among authors: renner s. Nat Chem Biol. 2009 Aug;5(8):581-3. doi: 10.1038/nchembio.187. Epub 2009 Jun 28. Nat Chem Biol. 2009. PMID: 19561620
Bioactivity-guided mapping and navigation of chemical space.
Renner S, van Otterlo WA, Dominguez Seoane M, Möcklinghoff S, Hofmann B, Wetzel S, Schuffenhauer A, Ertl P, Oprea TI, Steinhilber D, Brunsveld L, Rauh D, Waldmann H. Renner S, et al. Nat Chem Biol. 2009 Aug;5(8):585-92. doi: 10.1038/nchembio.188. Epub 2009 Jun 28. Nat Chem Biol. 2009. PMID: 19561619
533 results