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Targeting Cancer Metabolism Breaks Radioresistance by Impairing the Stress Response.
Schwab M, Thunborg K, Azimzadeh O, von Toerne C, Werner C, Shevtsov M, Di Genio T, Zdralevic M, Pouyssegur J, Renner K, Kreutz M, Multhoff G. Schwab M, et al. Among authors: renner k. Cancers (Basel). 2021 Jul 27;13(15):3762. doi: 10.3390/cancers13153762. Cancers (Basel). 2021. PMID: 34359663 Free PMC article.
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes.
Dietl K, Renner K, Dettmer K, Timischl B, Eberhart K, Dorn C, Hellerbrand C, Kastenberger M, Kunz-Schughart LA, Oefner PJ, Andreesen R, Gottfried E, Kreutz MP. Dietl K, et al. Among authors: renner k. J Immunol. 2010 Feb 1;184(3):1200-9. doi: 10.4049/jimmunol.0902584. Epub 2009 Dec 21. J Immunol. 2010. PMID: 20026743
New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells.
Gottfried E, Lang SA, Renner K, Bosserhoff A, Gronwald W, Rehli M, Einhell S, Gedig I, Singer K, Seilbeck A, Mackensen A, Grauer O, Hau P, Dettmer K, Andreesen R, Oefner PJ, Kreutz M. Gottfried E, et al. Among authors: renner k. PLoS One. 2013 Jul 9;8(7):e66987. doi: 10.1371/journal.pone.0066987. Print 2013. PLoS One. 2013. PMID: 23874405 Free PMC article.
Transcription and enhancer profiling in human monocyte subsets.
Schmidl C, Renner K, Peter K, Eder R, Lassmann T, Balwierz PJ, Itoh M, Nagao-Sato S, Kawaji H, Carninci P, Suzuki H, Hayashizaki Y, Andreesen R, Hume DA, Hoffmann P, Forrest AR, Kreutz MP, Edinger M, Rehli M; FANTOM consortium. Schmidl C, et al. Among authors: renner k. Blood. 2014 Apr 24;123(17):e90-9. doi: 10.1182/blood-2013-02-484188. Epub 2014 Mar 26. Blood. 2014. PMID: 24671955 Free article.
Metabolic plasticity of human T cells: Preserved cytokine production under glucose deprivation or mitochondrial restriction, but 2-deoxy-glucose affects effector functions.
Renner K, Geiselhöringer AL, Fante M, Bruss C, Färber S, Schönhammer G, Peter K, Singer K, Andreesen R, Hoffmann P, Oefner P, Herr W, Kreutz M. Renner K, et al. Eur J Immunol. 2015 Sep;45(9):2504-16. doi: 10.1002/eji.201545473. Epub 2015 Jul 20. Eur J Immunol. 2015. PMID: 26114249 Free article.
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.
Brand A, Singer K, Koehl GE, Kolitzus M, Schoenhammer G, Thiel A, Matos C, Bruss C, Klobuch S, Peter K, Kastenberger M, Bogdan C, Schleicher U, Mackensen A, Ullrich E, Fichtner-Feigl S, Kesselring R, Mack M, Ritter U, Schmid M, Blank C, Dettmer K, Oefner PJ, Hoffmann P, Walenta S, Geissler EK, Pouyssegur J, Villunger A, Steven A, Seliger B, Schreml S, Haferkamp S, Kohl E, Karrer S, Berneburg M, Herr W, Mueller-Klieser W, Renner K, Kreutz M. Brand A, et al. Among authors: renner k. Cell Metab. 2016 Nov 8;24(5):657-671. doi: 10.1016/j.cmet.2016.08.011. Epub 2016 Sep 15. Cell Metab. 2016. PMID: 27641098 Free article.
D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization.
Böttcher M, Renner K, Berger R, Mentz K, Thomas S, Cardenas-Conejo ZE, Dettmer K, Oefner PJ, Mackensen A, Kreutz M, Mougiakakos D. Böttcher M, et al. Among authors: renner k. Oncoimmunology. 2018 Mar 26;7(7):e1445454. doi: 10.1080/2162402X.2018.1445454. eCollection 2018. Oncoimmunology. 2018. PMID: 29900057 Free PMC article.
Targeting tumor-associated acidity in cancer immunotherapy.
Lacroix R, Rozeman EA, Kreutz M, Renner K, Blank CU. Lacroix R, et al. Among authors: renner k. Cancer Immunol Immunother. 2018 Sep;67(9):1331-1348. doi: 10.1007/s00262-018-2195-z. Epub 2018 Jul 5. Cancer Immunol Immunother. 2018. PMID: 29974196 Free PMC article. Review.
343 results