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Pfs230 yields higher malaria transmission-blocking vaccine activity than Pfs25 in humans but not mice.
Healy SA, Anderson C, Swihart BJ, Mwakingwe A, Gabriel EE, Decederfelt H, Hobbs CV, Rausch KM, Zhu D, Muratova O, Herrera R, Scaria PV, MacDonald NJ, Lambert LE, Zaidi I, Coelho CH, Renn JP, Wu Y, Narum DL, Duffy PE. Healy SA, et al. Among authors: renn jp. J Clin Invest. 2021 Apr 1;131(7):e146221. doi: 10.1172/JCI146221. J Clin Invest. 2021. PMID: 33561016 Free PMC article. Clinical Trial.
A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.
Coelho CH, Tang WK, Burkhardt M, Galson JD, Muratova O, Salinas ND, Alves E Silva TL, Reiter K, MacDonald NJ, Nguyen V, Herrera R, Shimp R, Narum DL, Byrne-Steele M, Pan W, Hou X, Brown B, Eisenhower M, Han J, Jenkins BJ, Doritchamou JYA, Smelkinson MG, Vega-Rodríguez J, Trück J, Taylor JJ, Sagara I, Healy SA, Renn JP, Tolia NH, Duffy PE. Coelho CH, et al. Among authors: renn jp. Nat Commun. 2021 Mar 19;12(1):1750. doi: 10.1038/s41467-021-21955-1. Nat Commun. 2021. PMID: 33741942 Free PMC article.
Plasmodium Preerythrocytic Vaccine Antigens Enhance Sterile Protection in Mice Induced by Circumsporozoite Protein.
Daniel S, Pichugin A, Torano H, Renn JP, Kwan J, Cowles MV, Conteh S, Lambert LE, Alani N, MacDonald NJ, Dai W, Highsmith K, Anderson C, Gorres JP, Musgrove J, Butler B, Althubaiti N, Dixit S, Zarling-Bejma S, Krzych U, Duffy PE. Daniel S, et al. Among authors: renn jp. Infect Immun. 2021 Oct 15;89(11):e0016521. doi: 10.1128/IAI.00165-21. Epub 2021 Jul 26. Infect Immun. 2021. PMID: 34310889 Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus 2 Seroassay Performance and Optimization in a Population With High Background Reactivity in Mali.
Woodford J, Sagara I, Dicko A, Zeguime A, Doucoure M, Kwan J, Zaidi I, Doritchamou J, Snow-Smith M, Alani N, Renn J, Kosik I, Holly J, Yewdell J, Esposito D, Sadtler K, Duffy P. Woodford J, et al. J Infect Dis. 2021 Dec 15;224(12):2001-2009. doi: 10.1093/infdis/jiab498. J Infect Dis. 2021. PMID: 34612499 Free PMC article.
Author Correction: Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity.
Renn JP, Doritchamou JYA, Tentokam BCN, Morrison RD, Cowles MV, Burkhardt M, Ma R, Mahamar A, Attaher O, Diarra BS, Traore M, Dicko A, Tolia NH, Fried M, Duffy PE. Renn JP, et al. Commun Biol. 2022 Apr 26;5(1):404. doi: 10.1038/s42003-022-03337-5. Commun Biol. 2022. PMID: 35474125 Free PMC article. No abstract available.
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