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Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization.
Wang B, Asarnow D, Lee WH, Huang CW, Faust B, Ng PML, Ngoh EZX, Bohn M, Bulkley D, Pizzorno A, Tan HC, Lee CY, Minhat RA, Terrier O, Soh MK, Teo FJ, Yeap YYC, Hu Y, Seah SGK, Maurer-Stroh S, Renia L, Hanson BJ, Rosa-Calatrava M, Manglik A, Cheng Y, Craik CS, Wang CI. Wang B, et al. Among authors: renia l. bioRxiv [Preprint]. 2020 Jul 15:2020.07.14.203414. doi: 10.1101/2020.07.14.203414. bioRxiv. 2020. PMID: 32699850 Free PMC article. Preprint.
Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients.
Poh CM, Carissimo G, Wang B, Amrun SN, Lee CY, Chee RS, Fong SW, Yeo NK, Lee WH, Torres-Ruesta A, Leo YS, Chen MI, Tan SY, Chai LYA, Kalimuddin S, Kheng SSG, Thien SY, Young BE, Lye DC, Hanson BJ, Wang CI, Renia L, Ng LFP. Poh CM, et al. Among authors: renia l. Nat Commun. 2020 Jun 1;11(1):2806. doi: 10.1038/s41467-020-16638-2. Nat Commun. 2020. PMID: 32483236 Free PMC article.
Asymptomatic COVID-19: disease tolerance with efficient anti-viral immunity against SARS-CoV-2.
Chan YH, Fong SW, Poh CM, Carissimo G, Yeo NK, Amrun SN, Goh YS, Lim J, Xu W, Chee RS, Torres-Ruesta A, Lee CY, Tay MZ, Chang ZW, Lee WH, Wang B, Tan SY, Kalimuddin S, Young BE, Leo YS, Wang CI, Lee B, Rötzschke O, Lye DC, Renia L, Ng LFP. Chan YH, et al. Among authors: renia l. EMBO Mol Med. 2021 Jun 7;13(6):e14045. doi: 10.15252/emmm.202114045. Epub 2021 May 27. EMBO Mol Med. 2021. PMID: 33961735 Free PMC article.
Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Asarnow D, Wang B, Lee WH, Hu Y, Huang CW, Faust B, Ng PML, Ngoh EZX, Bohn M, Bulkley D, Pizzorno A, Ary B, Tan HC, Lee CY, Minhat RA, Terrier O, Soh MK, Teo FJ, Yeap YYC, Seah SGK, Chan CEZ, Connelly E, Young NJ, Maurer-Stroh S, Renia L, Hanson BJ, Rosa-Calatrava M, Manglik A, Cheng Y, Craik CS, Wang CI. Asarnow D, et al. Among authors: renia l. Cell. 2021 Jun 10;184(12):3192-3204.e16. doi: 10.1016/j.cell.2021.04.033. Epub 2021 Apr 24. Cell. 2021. PMID: 33974910 Free PMC article.
Resistance of SARS-CoV-2 Delta variant to neutralization by BNT162b2-elicited antibodies in Asians.
Wang B, Goh YS, Fong SW, Young BE, Ngoh EZX, Chavatte JM, Salleh SNM, Yeo NK, Amrun SN, Hor PX, Loh CY, Lee CY, Chan YH, Chang ZW, Tay MZ, Rouers A, Torres-Ruesta A, Carissimo G, Soh MK, Lee RTC, Xu Y, Pada S, Lin RTP, Leo YS, Lye DC, Maurer-Stroh S, Ng LFP, Renia L, Wang CI. Wang B, et al. Among authors: renia l. Lancet Reg Health West Pac. 2021 Oct;15:100276. doi: 10.1016/j.lanwpc.2021.100276. Epub 2021 Sep 20. Lancet Reg Health West Pac. 2021. PMID: 34568853 Free PMC article. No abstract available.
Decreased memory B cell frequencies in COVID-19 delta variant vaccine breakthrough infection.
Tay MZ, Rouers A, Fong SW, Goh YS, Chan YH, Chang ZW, Xu W, Tan CW, Chia WN, Torres-Ruesta A, Amrun SN, Huang Y, Hor PX, Loh CY, Yeo NK, Wang B, Ngoh EZX, Salleh SNM, Chavatte JM, Lim AJ, Maurer-Stroh S, Wang LF, Lin RVTP, Wang CI, Tan SY, Young BE, Leo YS, Lye DC, Renia L, Ng LF. Tay MZ, et al. Among authors: renia l. EMBO Mol Med. 2022 Mar 7;14(3):e15227. doi: 10.15252/emmm.202115227. Epub 2022 Jan 21. EMBO Mol Med. 2022. PMID: 34994081 Free PMC article.
Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine.
Goh YS, Fong SW, Rouers A, Chang ZW, Tay MZ, Chavatte JM, Zhuo NZ, Hor PX, Loh CY, Huang Y, Wong JXE, Tan YJ, Lim DRX, Wang B, Ngoh EZX, Salleh SNM, Lee RTC, Pada S, Sun LJ, Ong DLS, Somani J, Lee ES; NCID Study Group; COVID‐19 Study Group; Maurer-Stroh S, Wang CI, Leo YS, Lin RT, Ren EC, Lye DC, Young BE, Lim PL, Ng LF, Renia L. Goh YS, et al. Among authors: renia l. Clin Transl Immunology. 2022 Aug 23;11(8):e1403. doi: 10.1002/cti2.1403. eCollection 2022. Clin Transl Immunology. 2022. PMID: 36016852 Free PMC article.
409 results