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Spiroindolones, a potent compound class for the treatment of malaria.
Rottmann M, McNamara C, Yeung BK, Lee MC, Zou B, Russell B, Seitz P, Plouffe DM, Dharia NV, Tan J, Cohen SB, Spencer KR, González-Páez GE, Lakshminarayana SB, Goh A, Suwanarusk R, Jegla T, Schmitt EK, Beck HP, Brun R, Nosten F, Renia L, Dartois V, Keller TH, Fidock DA, Winzeler EA, Diagana TT. Rottmann M, et al. Among authors: renia l. Science. 2010 Sep 3;329(5996):1175-80. doi: 10.1126/science.1193225. Science. 2010. PMID: 20813948 Free PMC article.
Plasmodium vivax susceptibility to ferroquine.
Leimanis ML, Jaidee A, Sriprawat K, Kaewpongsri S, Suwanarusk R, Barends M, Phyo AP, Russell B, Renia L, Nosten F. Leimanis ML, et al. Among authors: renia l. Antimicrob Agents Chemother. 2010 May;54(5):2228-30. doi: 10.1128/AAC.01572-09. Epub 2010 Mar 22. Antimicrob Agents Chemother. 2010. PMID: 20308387 Free PMC article.
On the cytoadhesion of Plasmodium vivax-infected erythrocytes.
Carvalho BO, Lopes SC, Nogueira PA, Orlandi PP, Bargieri DY, Blanco YC, Mamoni R, Leite JA, Rodrigues MM, Soares IS, Oliveira TR, Wunderlich G, Lacerda MV, del Portillo HA, Araújo MO, Russell B, Suwanarusk R, Snounou G, Rénia L, Costa FT. Carvalho BO, et al. Among authors: renia l. J Infect Dis. 2010 Aug 15;202(4):638-47. doi: 10.1086/654815. J Infect Dis. 2010. PMID: 20617923
The presence of leukocytes in ex vivo assays significantly increases the 50-percent inhibitory concentrations of artesunate and chloroquine against Plasmodium vivax and Plasmodium falciparum.
Kaewpongsri S, Sriprawat K, Suwanarusk R, Kyle DE, Lek-Uthai U, Leimanis M, Lwin KM, Phyo AP, Zwang J, Russell B, Nosten F, Renia L. Kaewpongsri S, et al. Among authors: renia l. Antimicrob Agents Chemother. 2011 Mar;55(3):1300-4. doi: 10.1128/AAC.01103-10. Epub 2010 Dec 28. Antimicrob Agents Chemother. 2011. PMID: 21189344 Free PMC article.
Methotrexate is highly potent against pyrimethamine-resistant Plasmodium vivax.
Imwong M, Russell B, Suwanarusk R, Nzila A, Leimanis ML, Sriprawat K, Kaewpongsri S, Phyo AP, Snounou G, Nosten F, Renia L. Imwong M, et al. Among authors: renia l. J Infect Dis. 2011 Jan 15;203(2):207-10. doi: 10.1093/infdis/jiq024. Epub 2010 Dec 9. J Infect Dis. 2011. PMID: 21288820 Free PMC article.
409 results