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2006 1
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18 results

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Page 1
(+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand-results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer's disease and healthy controls.
Tiepolt S, Becker GA, Wilke S, Cecchin D, Rullmann M, Meyer PM, Barthel H, Hesse S, Patt M, Luthardt J, Wagenknecht G, Sattler B, Deuther-Conrad W, Ludwig FA, Fischer S, Gertz HJ, Smits R, Hoepping A, Steinbach J, Brust P, Sabri O. Tiepolt S, et al. Among authors: smits r. Eur J Nucl Med Mol Imaging. 2021 Mar;48(3):731-746. doi: 10.1007/s00259-020-05029-w. Epub 2020 Sep 16. Eur J Nucl Med Mol Imaging. 2021. PMID: 32935187 Free PMC article.
Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer's dementia.
Sabri O, Meyer PM, Gräf S, Hesse S, Wilke S, Becker GA, Rullmann M, Patt M, Luthardt J, Wagenknecht G, Hoepping A, Smits R, Franke A, Sattler B, Tiepolt S, Fischer S, Deuther-Conrad W, Hegerl U, Barthel H, Schönknecht P, Brust P. Sabri O, et al. Among authors: smits r. Brain. 2018 Jun 1;141(6):1840-1854. doi: 10.1093/brain/awy099. Brain. 2018. PMID: 29672680 Free PMC article.
Procedures for the GMP-Compliant Production and Quality Control of [18F]PSMA-1007: A Next Generation Radiofluorinated Tracer for the Detection of Prostate Cancer.
Cardinale J, Martin R, Remde Y, Schäfer M, Hienzsch A, Hübner S, Zerges AM, Marx H, Hesse R, Weber K, Smits R, Hoepping A, Müller M, Neels OC, Kopka K. Cardinale J, et al. Among authors: smits r. Pharmaceuticals (Basel). 2017 Sep 27;10(4):77. doi: 10.3390/ph10040077. Pharmaceuticals (Basel). 2017. PMID: 28953234 Free PMC article.
Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results.
Kranz M, Sattler B, Tiepolt S, Wilke S, Deuther-Conrad W, Donat CK, Fischer S, Patt M, Schildan A, Patt J, Smits R, Hoepping A, Steinbach J, Sabri O, Brust P. Kranz M, et al. Among authors: smits r. EJNMMI Phys. 2016 Dec;3(1):25. doi: 10.1186/s40658-016-0160-5. Epub 2016 Oct 21. EJNMMI Phys. 2016. PMID: 27770429 Free PMC article.
LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors.
Ludwig FA, Smits R, Fischer S, Donat CK, Hoepping A, Brust P, Steinbach J. Ludwig FA, et al. Among authors: smits r. Molecules. 2016 Sep 8;21(9):1200. doi: 10.3390/molecules21091200. Molecules. 2016. PMID: 27617996 Free PMC article.
Enhanced copper-mediated (18)F-fluorination of aryl boronic esters provides eight radiotracers for PET applications.
Preshlock S, Calderwood S, Verhoog S, Tredwell M, Huiban M, Hienzsch A, Gruber S, Wilson TC, Taylor NJ, Cailly T, Schedler M, Collier TL, Passchier J, Smits R, Mollitor J, Hoepping A, Mueller M, Genicot C, Mercier J, Gouverneur V. Preshlock S, et al. Among authors: smits r. Chem Commun (Camb). 2016 Jun 28;52(54):8361-4. doi: 10.1039/c6cc03295h. Chem Commun (Camb). 2016. PMID: 27241832
Development of a Novel Nonpeptidic (18)F-Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission Tomography.
Wenzel B, Mollitor J, Deuther-Conrad W, Dukic-Stefanovic S, Kranz M, Vraka C, Teodoro R, Günther R, Donat CK, Ludwig FA, Fischer S, Smits R, Wadsak W, Mitterhauser M, Steinbach J, Hoepping A, Brust P. Wenzel B, et al. Among authors: smits r. J Med Chem. 2016 Mar 10;59(5):1800-17. doi: 10.1021/acs.jmedchem.5b01080. Epub 2016 Feb 3. J Med Chem. 2016. PMID: 26796795
First-in-human PET quantification study of cerebral α4β2* nicotinic acetylcholine receptors using the novel specific radioligand (-)-[(18)F]Flubatine.
Sabri O, Becker GA, Meyer PM, Hesse S, Wilke S, Graef S, Patt M, Luthardt J, Wagenknecht G, Hoepping A, Smits R, Franke A, Sattler B, Habermann B, Neuhaus P, Fischer S, Tiepolt S, Deuther-Conrad W, Barthel H, Schönknecht P, Brust P. Sabri O, et al. Among authors: smits r. Neuroimage. 2015 Sep;118:199-208. doi: 10.1016/j.neuroimage.2015.05.065. Epub 2015 May 30. Neuroimage. 2015. PMID: 26037057
18 results