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The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis.
Stoup N, Liberelle M, Schulz C, Cavdarli S, Vasseur R, Magnez R, Lahdaoui F, Skrypek N, Peretti F, Frénois F, Thuru X, Melnyk P, Renault N, Jonckheere N, Lebègue N, Van Seuningen I. Stoup N, et al. Among authors: renault n. Cancers (Basel). 2021 Nov 16;13(22):5746. doi: 10.3390/cancers13225746. Cancers (Basel). 2021. PMID: 34830899 Free PMC article.
Synthesis and Biological Evaluation of N-[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity.
Segaoula Z, Leclercq J, Verones V, Flouquet N, Lecoeur M, Ach L, Renault N, Barczyk A, Melnyk P, Berthelot P, Thuru X, Lebegue N. Segaoula Z, et al. Among authors: renault n. J Med Chem. 2016 Sep 22;59(18):8422-40. doi: 10.1021/acs.jmedchem.6b00847. Epub 2016 Aug 30. J Med Chem. 2016. PMID: 27538123 Free article.
Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.
Gibault F, Coevoet M, Sturbaut M, Farce A, Renault N, Allemand F, Guichou JF, Drucbert AS, Foulon C, Magnez R, Thuru X, Corvaisier M, Huet G, Chavatte P, Melnyk P, Bailly F, Cotelle P. Gibault F, et al. Among authors: renault n. Cancers (Basel). 2018 May 8;10(5):140. doi: 10.3390/cancers10050140. Cancers (Basel). 2018. PMID: 29738494 Free PMC article.
A phenotypic approach to the discovery of compounds that promote non-amyloidogenic processing of the amyloid precursor protein: Toward a new profile of indirect β-secretase inhibitors.
Gay M, Evrard C, Descamps F, Carato P, Renault N, Coevoet M, Eddarkaoui S, Baud C, Larchanché PE, Buée L, El Bakali J, Vingtdeux V, Sergeant N, Melnyk P. Gay M, et al. Among authors: renault n. Eur J Med Chem. 2018 Nov 5;159:104-125. doi: 10.1016/j.ejmech.2018.08.092. Epub 2018 Sep 22. Eur J Med Chem. 2018. PMID: 30268822
Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs.
Liberelle M, Toulotte F, Renault N, Gelin M, Allemand F, Melnyk P, Guichou JF, Cotelle P. Liberelle M, et al. Among authors: renault n. J Med Chem. 2022 Apr 28;65(8):5926-5940. doi: 10.1021/acs.jmedchem.2c00075. Epub 2022 Apr 7. J Med Chem. 2022. PMID: 35389210 Review.
Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction.
Le Biannic R, Magnez R, Klupsch F, Leleu-Chavain N, Thiroux B, Tardy M, El Bouazzati H, Dezitter X, Renault N, Vergoten G, Bailly C, Quesnel B, Thuru X, Millet R. Le Biannic R, et al. Among authors: renault n. Eur J Med Chem. 2022 Jun 5;236:114343. doi: 10.1016/j.ejmech.2022.114343. Epub 2022 Apr 4. Eur J Med Chem. 2022. PMID: 35429911
High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists.
Bolteau R, Duroux R, Laversin A, Vreulz B, Shiriaeva A, Stauch B, Han GW, Cherezov V, Renault N, Barczyk A, Ravez S, Coevoet M, Melnyk P, Liberelle M, Yous S. Bolteau R, et al. Among authors: renault n. Eur J Med Chem. 2022 Nov 5;241:114620. doi: 10.1016/j.ejmech.2022.114620. Epub 2022 Jul 22. Eur J Med Chem. 2022. PMID: 35933788
81 results