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Sclerostin antibody preserves the morphology and structure of osteocytes and blocks the severe skeletal deterioration after motor-complete spinal cord injury in rats.
Qin W, Li X, Peng Y, Harlow LM, Ren Y, Wu Y, Li J, Qin Y, Sun J, Zheng S, Brown T, Feng JQ, Ke HZ, Bauman WA, Cardozo CC. Qin W, et al. Among authors: ren y. J Bone Miner Res. 2015 Nov;30(11):1994-2004. doi: 10.1002/jbmr.2549. Epub 2015 Jun 10. J Bone Miner Res. 2015. PMID: 25974843 Free article.
G protein-coupled receptor kinase 3 modulates mesenchymal stem cell proliferation and differentiation through sphingosine-1-phosphate receptor regulation.
Brozowski JM, Timoshchenko RG, Serafin DS, Allyn B, Koontz J, Rabjohns EM, Rampersad RR, Ren Y, Eudy AM, Harris TF, Abraham D, Mattox D, Rubin CT, Hilton MJ, Rubin J, Allbritton NL, Billard MJ, Tarrant TK. Brozowski JM, et al. Among authors: ren y. Stem Cell Res Ther. 2022 Jan 29;13(1):37. doi: 10.1186/s13287-022-02715-4. Stem Cell Res Ther. 2022. PMID: 35093170 Free PMC article.
Osteocytes but not osteoblasts directly build mineralized bone structures.
Wang K, Ren Y, Lin S, Jing Y, Ma C, Wang J, Yuan XB, Han X, Zhao H, Wang Z, Zheng M, Xiao Y, Chen L, Olsen BR, Feng JQ. Wang K, et al. Among authors: ren y. Int J Biol Sci. 2021 Jun 11;17(10):2430-2448. doi: 10.7150/ijbs.61012. eCollection 2021. Int J Biol Sci. 2021. PMID: 34326685 Free PMC article.
Aged G Protein-Coupled Receptor Kinase 3 (Grk3)-Deficient Mice Exhibit Enhanced Osteoclastogenesis and Develop Bone Lesions Analogous to Human Paget's Disease of Bone.
Rabjohns EM, Rampersad RR, Ghosh A, Hurst K, Eudy AM, Brozowski JM, Lee HH, Ren Y, Mirando A, Gladman J, Bowser JL, Berg K, Wani S, Ralston SH, Hilton MJ, Tarrant TK. Rabjohns EM, et al. Among authors: ren y. Cells. 2023 Mar 23;12(7):981. doi: 10.3390/cells12070981. Cells. 2023. PMID: 37048054 Free PMC article.
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