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hERG block potencies for 5 positive control drugs obtained per ICH E14/S7B Q&As best practices: Impact of recording temperature and drug loss.
Alvarez Baron C, Thiebaud N, Ren M, Viatchenko-Karpinski S, Indapurkar A, King T, Matta MK, Ismaiel OA, Patel V, Mashaee M, Vicente J, Wu WW. Alvarez Baron C, et al. Among authors: ren m. J Pharmacol Toxicol Methods. 2022 Sep-Oct;117:107193. doi: 10.1016/j.vascn.2022.107193. Epub 2022 Jul 2. J Pharmacol Toxicol Methods. 2022. PMID: 35792285 Free article.
Experimental factors that impact CaV1.2 channel pharmacology-Effects of recording temperature, charge carrier, and quantification of drug effects on the step and ramp currents elicited by the "step-step-ramp" voltage protocol.
Ren M, Randolph AL, Alvarez-Baron C, Guo D, Tran PN, Thiebaud N, Sheng J, Zhao J, Wu WW. Ren M, et al. PLoS One. 2022 Nov 23;17(11):e0276995. doi: 10.1371/journal.pone.0276995. eCollection 2022. PLoS One. 2022. PMID: 36417390 Free PMC article.
2,872 results