Remsberg J - Search Results

1

A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver.

Shabtai Y, Nagaraj NK, Batmanov K, Cho YW, Guan Y, Jiang C, Remsberg J, Forrest D, Lazar MA. Shabtai Y, et al. Among authors: remsberg j. Genes Dev. 2021 Mar 1;35(5-6):367-378. doi: 10.1101/gad.345686.120. Epub 2021 Feb 18. Genes Dev. 2021. PMID: 33602873 Free PMC article.

2

An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides.

Armour SM, Remsberg JR, Damle M, Sidoli S, Ho WY, Li Z, Garcia BA, Lazar MA. Armour SM, et al. Nat Commun. 2017 Sep 15;8(1):549. doi: 10.1038/s41467-017-00772-5. Nat Commun. 2017. PMID: 28916805 Free PMC article.

3

Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold.

Adlanmerini M, Carpenter BJ, Remsberg JR, Aubert Y, Peed LC, Richter HJ, Lazar MA. Adlanmerini M, et al. Among authors: remsberg jr. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18691-18699. doi: 10.1073/pnas.1909883116. Epub 2019 Aug 26. Proc Natl Acad Sci U S A. 2019. PMID: 31451658 Free PMC article.

4

GENE REGULATION. Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock.

Zhang Y, Fang B, Emmett MJ, Damle M, Sun Z, Feng D, Armour SM, Remsberg JR, Jager J, Soccio RE, Steger DJ, Lazar MA. Zhang Y, et al. Among authors: remsberg jr. Science. 2015 Jun 26;348(6242):1488-92. doi: 10.1126/science.aab3021. Epub 2015 Jun 4. Science. 2015. PMID: 26044300 Free PMC article.

5

Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion.

Remsberg JR, Ediger BN, Ho WY, Damle M, Li Z, Teng C, Lanzillotta C, Stoffers DA, Lazar MA. Remsberg JR, et al. Mol Metab. 2016 Nov 22;6(1):30-37. doi: 10.1016/j.molmet.2016.11.007. eCollection 2017 Jan. Mol Metab. 2016. PMID: 28123935 Free PMC article.

6

Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders.

Liu Z, Remsberg JR, Li H, Njomen E, DeMeester KE, Tao Y, Xia G, Hayward RE, Yoo M, Nguyen T, Simon GM, Schreiber SL, Melillo B, Cravatt BF. Liu Z, et al. Among authors: remsberg jr. J Am Chem Soc. 2024 Apr 17;146(15):10393-10406. doi: 10.1021/jacs.3c13448. Epub 2024 Apr 3. J Am Chem Soc. 2024. PMID: 38569115

7

Redirecting the pioneering function of FOXA1 with covalent small molecules.

Won SJ, Zhang Y, Reinhardt CJ, MacRae NS, DeMeester KE, Njomen E, Hargis LM, Remsberg JR, Melillo B, Cravatt BF, Erb MA. Won SJ, et al. Among authors: remsberg jr. bioRxiv [Preprint]. 2024 Mar 21:2024.03.21.586158. doi: 10.1101/2024.03.21.586158. bioRxiv. 2024. PMID: 38562719 Free PMC article. Preprint.

8

Chemical Proteomic Discovery of Isotype-Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2.

Tao Y, Felber JG, Zou Z, Njomen E, Remsberg JR, Ogasawara D, Ye C, Melillo B, Schreiber SL, He C, Remillard D, Cravatt BF. Tao Y, et al. Among authors: remsberg jr. Angew Chem Int Ed Engl. 2023 Dec 18;62(51):e202311924. doi: 10.1002/anie.202311924. Epub 2023 Nov 14. Angew Chem Int Ed Engl. 2023. PMID: 37909922

9

Assigning functionality to cysteines by base editing of cancer dependency genes.

Li H, Ma T, Remsberg JR, Won SJ, DeMeester KE, Njomen E, Ogasawara D, Zhao KT, Huang TP, Lu B, Simon GM, Melillo B, Schreiber SL, Lykke-Andersen J, Liu DR, Cravatt BF. Li H, et al. Among authors: remsberg jr. Nat Chem Biol. 2023 Nov;19(11):1320-1330. doi: 10.1038/s41589-023-01428-w. Epub 2023 Oct 2. Nat Chem Biol. 2023. PMID: 37783940 Free PMC article.

10

Proteomic discovery of chemical probes that perturb protein complexes in human cells.

Lazear MR, Remsberg JR, Jaeger MG, Rothamel K, Her HL, DeMeester KE, Njomen E, Hogg SJ, Rahman J, Whitby LR, Won SJ, Schafroth MA, Ogasawara D, Yokoyama M, Lindsey GL, Li H, Germain J, Barbas S, Vaughan J, Hanigan TW, Vartabedian VF, Reinhardt CJ, Dix MM, Koo SJ, Heo I, Teijaro JR, Simon GM, Ghosh B, Abdel-Wahab O, Ahn K, Saghatelian A, Melillo B, Schreiber SL, Yeo GW, Cravatt BF. Lazear MR, et al. Among authors: remsberg jr. Mol Cell. 2023 May 18;83(10):1725-1742.e12. doi: 10.1016/j.molcel.2023.03.026. Epub 2023 Apr 20. Mol Cell. 2023. PMID: 37084731

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