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"Inactive" ingredients in oral medications.
Reker D, Blum SM, Steiger C, Anger KE, Sommer JM, Fanikos J, Traverso G. Reker D, et al. Sci Transl Med. 2019 Mar 13;11(483):eaau6753. doi: 10.1126/scitranslmed.aau6753. Sci Transl Med. 2019. PMID: 30867323 Free PMC article. Review.
Machine Learning Uncovers Food- and Excipient-Drug Interactions.
Reker D, Shi Y, Kirtane AR, Hess K, Zhong GJ, Crane E, Lin CH, Langer R, Traverso G. Reker D, et al. Cell Rep. 2020 Mar 17;30(11):3710-3716.e4. doi: 10.1016/j.celrep.2020.02.094. Cell Rep. 2020. PMID: 32187543 Free PMC article.
Robotically handled whole-tissue culture system for the screening of oral drug formulations.
von Erlach T, Saxton S, Shi Y, Minahan D, Reker D, Javid F, Lee YL, Schoellhammer C, Esfandiary T, Cleveland C, Booth L, Lin J, Levy H, Blackburn S, Hayward A, Langer R, Traverso G. von Erlach T, et al. Among authors: reker d. Nat Biomed Eng. 2020 May;4(5):544-559. doi: 10.1038/s41551-020-0545-6. Epub 2020 Apr 27. Nat Biomed Eng. 2020. PMID: 32341538 Free PMC article.
Computationally guided high-throughput design of self-assembling drug nanoparticles.
Reker D, Rybakova Y, Kirtane AR, Cao R, Yang JW, Navamajiti N, Gardner A, Zhang RM, Esfandiary T, L'Heureux J, von Erlach T, Smekalova EM, Leboeuf D, Hess K, Lopes A, Rogner J, Collins J, Tamang SM, Ishida K, Chamberlain P, Yun D, Lytton-Jean A, Soule CK, Cheah JH, Hayward AM, Langer R, Traverso G. Reker D, et al. Nat Nanotechnol. 2021 Jun;16(6):725-733. doi: 10.1038/s41565-021-00870-y. Epub 2021 Mar 25. Nat Nanotechnol. 2021. PMID: 33767382 Free PMC article.
Dynamic Monitoring of Systemic Biomarkers with Gastric Sensors.
Steiger C, Phan NV, Huang HW, Sun H, Chu JN, Reker D, Gwynne D, Collins J, Tamang S, McManus R, Lopes A, Hayward A, Baron RM, Kim EY, Traverso G. Steiger C, et al. Among authors: reker d. Adv Sci (Weinh). 2021 Dec;8(24):e2102861. doi: 10.1002/advs.202102861. Epub 2021 Oct 28. Adv Sci (Weinh). 2021. PMID: 34713599 Free PMC article.
Screening oral drugs for their interactions with the intestinal transportome via porcine tissue explants and machine learning.
Shi Y, Reker D, Byrne JD, Kirtane AR, Hess K, Wang Z, Navamajiti N, Young CC, Fralish Z, Zhang Z, Lopes A, Soares V, Wainer J, von Erlach T, Miao L, Langer R, Traverso G. Shi Y, et al. Among authors: reker d. Nat Biomed Eng. 2024 Mar;8(3):278-290. doi: 10.1038/s41551-023-01128-9. Epub 2024 Feb 20. Nat Biomed Eng. 2024. PMID: 38378821
114 results