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Mirror-image ligand discovery enabled by single-shot fast-flow synthesis of D-proteins.
Callahan AJ, Gandhesiri S, Travaline TL, Reja RM, Lozano Salazar L, Hanna S, Lee YC, Li K, Tokareva OS, Swiecicki JM, Loas A, Verdine GL, McGee JH, Pentelute BL. Callahan AJ, et al. Among authors: reja rm. Nat Commun. 2024 Feb 28;15(1):1813. doi: 10.1038/s41467-024-45634-z. Nat Commun. 2024. PMID: 38418820 Free PMC article.
A cationic amphiphilic peptide chaperone rescues Aβ42 aggregation and cytotoxicity.
Puneeth Kumar DR, Reja RM, Senapati DK, Singh M, Nalawade SA, George G, Kaul G, Akhir A, Chopra S, Raghothama S, Gopi HN. Puneeth Kumar DR, et al. Among authors: reja rm. RSC Med Chem. 2022 Dec 10;14(2):332-340. doi: 10.1039/d2md00414c. eCollection 2023 Feb 22. RSC Med Chem. 2022. PMID: 36846376 Free PMC article.
Structural insight into hybrid peptide ε-helices.
Misra R, George G, Reja RM, Dey S, Raghothama S, Gopi HN. Misra R, et al. Among authors: reja rm. Chem Commun (Camb). 2020 Feb 18;56(14):2171-2173. doi: 10.1039/c9cc07413a. Epub 2020 Jan 23. Chem Commun (Camb). 2020. PMID: 31970340
Artificial β-Double Helices from Achiral γ-Peptides.
Misra R, Dey S, Reja RM, Gopi HN. Misra R, et al. Among authors: reja rm. Angew Chem Int Ed Engl. 2018 Jan 22;57(4):1057-1061. doi: 10.1002/anie.201711124. Epub 2017 Dec 27. Angew Chem Int Ed Engl. 2018. PMID: 29194908
13 results