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Chemical synthesis, backbone cyclization and oxidative folding of cystine-knot peptides: promising scaffolds for applications in drug design.
Molecules. 2012 Oct 24;17(11):12533-52. doi: 10.3390/molecules171112533.
Molecules. 2012.
PMID: 23095896
Free PMC article.
Review.
Oxidative folding of peptides with cystine-knot architectures: kinetic studies and optimization of folding conditions.
Reinwarth M, Glotzbach B, Tomaszowski M, Fabritz S, Avrutina O, Kolmar H.
Reinwarth M, et al.
Chembiochem. 2013 Jan 2;14(1):137-46. doi: 10.1002/cbic.201200604. Epub 2012 Dec 11.
Chembiochem. 2013.
PMID: 23229141
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Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1.
Glotzbach B, Reinwarth M, Weber N, Fabritz S, Tomaszowski M, Fittler H, Christmann A, Avrutina O, Kolmar H.
Glotzbach B, et al. Among authors: reinwarth m.
PLoS One. 2013 Oct 11;8(10):e76956. doi: 10.1371/journal.pone.0076956. eCollection 2013.
PLoS One. 2013.
PMID: 24146945
Free PMC article.
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Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins.
Reinwarth M, Avrutina O, Fabritz S, Kolmar H.
Reinwarth M, et al.
PLoS One. 2014 Oct 10;9(10):e108626. doi: 10.1371/journal.pone.0108626. eCollection 2014.
PLoS One. 2014.
PMID: 25303319
Free PMC article.
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"Triazole bridge": disulfide-bond replacement by ruthenium-catalyzed formation of 1,5-disubstituted 1,2,3-triazoles.
Empting M, Avrutina O, Meusinger R, Fabritz S, Reinwarth M, Biesalski M, Voigt S, Buntkowsky G, Kolmar H.
Empting M, et al. Among authors: reinwarth m.
Angew Chem Int Ed Engl. 2011 May 23;50(22):5207-11. doi: 10.1002/anie.201008142. Epub 2011 May 4.
Angew Chem Int Ed Engl. 2011.
PMID: 21544910
No abstract available.
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From pico to nano: biofunctionalization of cube-octameric silsesquioxanes by peptides and miniproteins.
Fabritz S, Hörner S, Könning D, Empting M, Reinwarth M, Dietz C, Glotzbach B, Frauendorf H, Kolmar H, Avrutina O.
Fabritz S, et al. Among authors: reinwarth m.
Org Biomol Chem. 2012 Aug 21;10(31):6287-93. doi: 10.1039/c2ob25728a. Epub 2012 Jun 26.
Org Biomol Chem. 2012.
PMID: 22733169
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Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).
Maaß F, Wüstehube-Lausch J, Dickgießer S, Valldorf B, Reinwarth M, Schmoldt HU, Daneschdar M, Avrutina O, Sahin U, Kolmar H.
Maaß F, et al. Among authors: reinwarth m.
J Pept Sci. 2015 Aug;21(8):651-60. doi: 10.1002/psc.2782. Epub 2015 May 10.
J Pept Sci. 2015.
PMID: 25964162
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Structural characterization of Spinacia oleracea trypsin inhibitor III (SOTI-III).
Glotzbach B, Schmelz S, Reinwarth M, Christmann A, Heinz DW, Kolmar H.
Glotzbach B, et al. Among authors: reinwarth m.
Acta Crystallogr D Biol Crystallogr. 2013 Jan;69(Pt 1):114-20. doi: 10.1107/S0907444912043880. Epub 2012 Dec 20.
Acta Crystallogr D Biol Crystallogr. 2013.
PMID: 23275169
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