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A new model system identifies epidermal growth factor receptor-human epidermal growth factor receptor 2 (HER2) and HER2-human epidermal growth factor receptor 3 heterodimers as potent inducers of oesophageal epithelial cell invasion.
Fichter CD, Przypadlo CM, Buck A, Herbener N, Riedel B, Schäfer L, Nakagawa H, Walch A, Reinheckel T, Werner M, Lassmann S. Fichter CD, et al. Among authors: reinheckel t. J Pathol. 2017 Dec;243(4):481-495. doi: 10.1002/path.4987. Epub 2017 Nov 5. J Pathol. 2017. PMID: 28940194 Free PMC article.
STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.
Timme S, Ihde S, Fichter CD, Waehle V, Bogatyreva L, Atanasov K, Kohler I, Schöpflin A, Geddert H, Faller G, Klimstra D, Tang L, Reinheckel T, Hauschke D, Busch H, Boerries M, Werner M, Lassmann S. Timme S, et al. Among authors: reinheckel t. Oncogene. 2014 Jun 19;33(25):3256-66. doi: 10.1038/onc.2013.298. Epub 2013 Aug 5. Oncogene. 2014. PMID: 23912451
MMP14 empowers tumor-initiating breast cancer cells under hypoxic nutrient-depleted conditions.
Hillebrand LE, Wickberg SM, Gomez-Auli A, Follo M, Maurer J, Busch H, Boerries M, Reinheckel T. Hillebrand LE, et al. Among authors: reinheckel t. FASEB J. 2019 Mar;33(3):4124-4140. doi: 10.1096/fj.201801127R. Epub 2018 Dec 6. FASEB J. 2019. PMID: 30521382
With the use of primary CD24(+)CD90(+)CD45(-) TICs from the mouse mammary tumor virus-polyoma middle T mouse breast cancer model, iTICs were generated by single cell-initiated sphere and subsequent 2-dimensional monolayer culture. ...M., Gomez-Auli, A., Follo, M., Maurer, …
With the use of primary CD24(+)CD90(+)CD45(-) TICs from the mouse mammary tumor virus-polyoma middle T mouse breast cancer model, iTI …
B-Raf deficiency impairs tumor initiation and progression in a murine breast cancer model.
Köhler M, Ehrenfeld S, Halbach S, Lauinger M, Burk U, Reischmann N, Cheng S, Spohr C, Uhl FM, Köhler N, Ringwald K, Braun S, Peters C, Zeiser R, Reinheckel T, Brummer T. Köhler M, et al. Among authors: reinheckel t. Oncogene. 2019 Feb;38(8):1324-1339. doi: 10.1038/s41388-018-0663-8. Epub 2019 Jan 18. Oncogene. 2019. PMID: 30659267
184 results