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Proteomic discovery of chemical probes that perturb protein complexes in human cells.
Lazear MR, Remsberg JR, Jaeger MG, Rothamel K, Her HL, DeMeester KE, Njomen E, Hogg SJ, Rahman J, Whitby LR, Won SJ, Schafroth MA, Ogasawara D, Yokoyama M, Lindsey GL, Li H, Germain J, Barbas S, Vaughan J, Hanigan TW, Vartabedian VF, Reinhardt CJ, Dix MM, Koo SJ, Heo I, Teijaro JR, Simon GM, Ghosh B, Abdel-Wahab O, Ahn K, Saghatelian A, Melillo B, Schreiber SL, Yeo GW, Cravatt BF. Lazear MR, et al. Among authors: reinhardt cj. Mol Cell. 2023 May 18;83(10):1725-1742.e12. doi: 10.1016/j.molcel.2023.03.026. Epub 2023 Apr 20. Mol Cell. 2023. PMID: 37084731
Redirecting the pioneering function of FOXA1 with covalent small molecules.
Won SJ, Zhang Y, Reinhardt CJ, MacRae NS, DeMeester KE, Njomen E, Hargis LM, Remsberg JR, Melillo B, Cravatt BF, Erb MA. Won SJ, et al. Among authors: reinhardt cj. bioRxiv [Preprint]. 2024 Mar 21:2024.03.21.586158. doi: 10.1101/2024.03.21.586158. bioRxiv. 2024. PMID: 38562719 Free PMC article. Preprint.
15 results