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The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia.
Ham DJ, Börsch A, Lin S, Thürkauf M, Weihrauch M, Reinhard JR, Delezie J, Battilana F, Wang X, Kaiser MS, Guridi M, Sinnreich M, Rich MM, Mittal N, Tintignac LA, Handschin C, Zavolan M, Rüegg MA. Ham DJ, et al. Among authors: reinhard jr. Nat Commun. 2020 Sep 9;11(1):4510. doi: 10.1038/s41467-020-18140-1. Nat Commun. 2020. PMID: 32908143 Free PMC article.
mTOR controls embryonic and adult myogenesis via mTORC1.
Rion N, Castets P, Lin S, Enderle L, Reinhard JR, Eickhorst C, Rüegg MA. Rion N, et al. Among authors: reinhard jr. Development. 2019 Apr 8;146(7):dev172460. doi: 10.1242/dev.172460. Development. 2019. PMID: 30872276
mTORC2 affects the maintenance of the muscle stem cell pool.
Rion N, Castets P, Lin S, Enderle L, Reinhard JR, Rüegg MA. Rion N, et al. Among authors: reinhard jr. Skelet Muscle. 2019 Dec 2;9(1):30. doi: 10.1186/s13395-019-0217-y. Skelet Muscle. 2019. PMID: 31791403 Free PMC article.
104 results