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STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses.
Vila IK, Chamma H, Steer A, Saccas M, Taffoni C, Turtoi E, Reinert LS, Hussain S, Marines J, Jin L, Bonnefont X, Hubert M, Schwartz O, Paludan SR, Van Simaeys G, Doumont G, Sobhian B, Vlachakis D, Turtoi A, Laguette N. Vila IK, et al. Among authors: reinert ls. Cell Metab. 2022 Jan 4;34(1):125-139.e8. doi: 10.1016/j.cmet.2021.12.007. Cell Metab. 2022. PMID: 34986331 Free PMC article.
TRAM is required for TLR2 endosomal signaling to type I IFN induction.
Stack J, Doyle SL, Connolly DJ, Reinert LS, O'Keeffe KM, McLoughlin RM, Paludan SR, Bowie AG. Stack J, et al. Among authors: reinert ls. J Immunol. 2014 Dec 15;193(12):6090-102. doi: 10.4049/jimmunol.1401605. Epub 2014 Nov 10. J Immunol. 2014. PMID: 25385819 Free PMC article.
Functional IRF3 deficiency in a patient with herpes simplex encephalitis.
Andersen LL, Mørk N, Reinert LS, Kofod-Olsen E, Narita R, Jørgensen SE, Skipper KA, Höning K, Gad HH, Østergaard L, Ørntoft TF, Hornung V, Paludan SR, Mikkelsen JG, Fujita T, Christiansen M, Hartmann R, Mogensen TH. Andersen LL, et al. Among authors: reinert ls. J Exp Med. 2015 Aug 24;212(9):1371-9. doi: 10.1084/jem.20142274. Epub 2015 Jul 27. J Exp Med. 2015. PMID: 26216125 Free PMC article.
HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression.
Christensen MH, Jensen SB, Miettinen JJ, Luecke S, Prabakaran T, Reinert LS, Mettenleiter T, Chen ZJ, Knipe DM, Sandri-Goldin RM, Enquist LW, Hartmann R, Mogensen TH, Rice SA, Nyman TA, Matikainen S, Paludan SR. Christensen MH, et al. Among authors: reinert ls. EMBO J. 2016 Jul 1;35(13):1385-99. doi: 10.15252/embj.201593458. Epub 2016 May 27. EMBO J. 2016. PMID: 27234299 Free PMC article.
45 results