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Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer.
Cho S, Zammarchi F, Williams DG, Havenith CEG, Monks NR, Tyrer P, D'Hooge F, Fleming R, Vashisht K, Dimasi N, Bertelli F, Corbett S, Adams L, Reinert HW, Dissanayake S, Britten CE, King W, Dacosta K, Tammali R, Schifferli K, Strout P, Korade M 3rd, Masson Hinrichs MJ, Chivers S, Corey E, Liu H, Kim S, Bander NH, Howard PW, Hartley JA, Coats S, Tice DA, Herbst R, van Berkel PH. Cho S, et al. Among authors: reinert hw. Mol Cancer Ther. 2018 Oct;17(10):2176-2186. doi: 10.1158/1535-7163.MCT-17-0982. Epub 2018 Jul 31. Mol Cancer Ther. 2018. PMID: 30065100
Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression.
Pye H, Butt MA, Funnell L, Reinert HW, Puccio I, Rehman Khan SU, Saouros S, Marklew JS, Stamati I, Qurashi M, Haidry R, Sehgal V, Oukrif D, Gandy M, Whitaker HC, Rodriguez-Justo M, Novelli M, Hamoudi R, Yahioglu G, Deonarain MP, Lovat LB. Pye H, et al. Among authors: reinert hw. Oncotarget. 2018 May 1;9(33):22945-22959. doi: 10.18632/oncotarget.25159. eCollection 2018 May 1. Oncotarget. 2018. PMID: 29796164 Free PMC article.
Upregulation of mucin glycoprotein MUC1 in the progression to esophageal adenocarcinoma and therapeutic potential with a targeted photoactive antibody-drug conjugate.
Adil Butt M, Pye H, Haidry RJ, Oukrif D, Khan SU, Puccio I, Gandy M, Reinert HW, Bloom E, Rashid M, Yahioglu G, Deonarain MP, Hamoudi R, Rodriguez-Justo M, Novelli MR, Lovat LB. Adil Butt M, et al. Among authors: reinert hw. Oncotarget. 2017 Apr 11;8(15):25080-25096. doi: 10.18632/oncotarget.15340. Oncotarget. 2017. PMID: 28212575 Free PMC article.
A HER2 selective theranostic agent for surgical resection guidance and photodynamic therapy.
Pye H, Butt MA, Reinert HW, Maruani A, Nunes JP, Marklew JS, Qurashi M, Funnell L, May A, Stamati I, Hamoudi R, Baker JR, Smith ME, Caddick S, Deonarain MP, Yahioglu G, Chudasama V, Lovat LB. Pye H, et al. Among authors: reinert hw. Photochem Photobiol Sci. 2016 Oct 5;15(10):1227-1238. doi: 10.1039/c6pp00139d. Epub 2016 Aug 9. Photochem Photobiol Sci. 2016. PMID: 27501936