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Hsp90 and FKBP51: complex regulators of psychiatric diseases.
Criado-Marrero M, Rein T, Binder EB, Porter JT, Koren J 3rd, Blair LJ. Criado-Marrero M, et al. Among authors: rein t. Philos Trans R Soc Lond B Biol Sci. 2018 Jan 19;373(1738):20160532. doi: 10.1098/rstb.2016.0532. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29203717 Free PMC article. Review.
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.
Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Pütz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Künzel HE, Fuchs B, Majer M, Pfennig A, Kern N, Brunner J, Modell S, Baghai T, Deiml T, Zill P, Bondy B, Rupprecht R, Messer T, Köhnlein O, Dabitz H, Brückl T, Müller N, Pfister H, Lieb R, Mueller JC, Lõhmussaar E, Strom TM, Bettecken T, Meitinger T, Uhr M, Rein T, Holsboer F, Muller-Myhsok B. Binder EB, et al. Among authors: rein t. Nat Genet. 2004 Dec;36(12):1319-25. doi: 10.1038/ng1479. Epub 2004 Nov 21. Nat Genet. 2004. PMID: 15565110
XAP2 inhibits glucocorticoid receptor activity in mammalian cells.
Laenger A, Lang-Rollin I, Kozany C, Zschocke J, Zimmermann N, Rüegg J, Holsboer F, Hausch F, Rein T. Laenger A, et al. Among authors: rein t. FEBS Lett. 2009 May 6;583(9):1493-8. doi: 10.1016/j.febslet.2009.03.072. Epub 2009 Apr 16. FEBS Lett. 2009. PMID: 19375531 Free article.
FK506 binding protein 5 shapes stress responsiveness: modulation of neuroendocrine reactivity and coping behavior.
Touma C, Gassen NC, Herrmann L, Cheung-Flynn J, Büll DR, Ionescu IA, Heinzmann JM, Knapman A, Siebertz A, Depping AM, Hartmann J, Hausch F, Schmidt MV, Holsboer F, Ising M, Cox MB, Schmidt U, Rein T. Touma C, et al. Among authors: rein t. Biol Psychiatry. 2011 Nov 15;70(10):928-36. doi: 10.1016/j.biopsych.2011.07.023. Epub 2011 Sep 10. Biol Psychiatry. 2011. PMID: 21907973
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions.
Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Pace TW, Mercer KB, Mayberg HS, Bradley B, Nemeroff CB, Holsboer F, Heim CM, Ressler KJ, Rein T, Binder EB. Klengel T, et al. Among authors: rein t. Nat Neurosci. 2013 Jan;16(1):33-41. doi: 10.1038/nn.3275. Epub 2012 Dec 2. Nat Neurosci. 2013. PMID: 23201972 Free PMC article.
Association of FKBP51 with priming of autophagy pathways and mediation of antidepressant treatment response: evidence in cells, mice, and humans.
Gassen NC, Hartmann J, Zschocke J, Stepan J, Hafner K, Zellner A, Kirmeier T, Kollmannsberger L, Wagner KV, Dedic N, Balsevich G, Deussing JM, Kloiber S, Lucae S, Holsboer F, Eder M, Uhr M, Ising M, Schmidt MV, Rein T. Gassen NC, et al. Among authors: rein t. PLoS Med. 2014 Nov 11;11(11):e1001755. doi: 10.1371/journal.pmed.1001755. eCollection 2014 Nov. PLoS Med. 2014. PMID: 25386878 Free PMC article.
140 results