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Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells.
Fang Z, Chen S, Manchanda Y, Bitsi S, Pickford P, David A, Shchepinova MM, Corrêa IR Jr, Hodson DJ, Broichhagen J, Tate EW, Reimann F, Salem V, Rutter GA, Tan T, Bloom SR, Tomas A, Jones B. Fang Z, et al. Among authors: reimann f. Int J Mol Sci. 2020 Nov 9;21(21):8404. doi: 10.3390/ijms21218404. Int J Mol Sci. 2020. PMID: 33182425 Free PMC article.
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.
Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA. Nicolson TJ, et al. Among authors: reimann f. Diabetes. 2009 Sep;58(9):2070-83. doi: 10.2337/db09-0551. Epub 2009 Jun 19. Diabetes. 2009. PMID: 19542200 Free PMC article.
Ablation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo.
Sun G, Tarasov AI, McGinty J, McDonald A, da Silva Xavier G, Gorman T, Marley A, French PM, Parker H, Gribble F, Reimann F, Prendiville O, Carzaniga R, Viollet B, Leclerc I, Rutter GA. Sun G, et al. Among authors: reimann f. Diabetologia. 2010 May;53(5):924-36. doi: 10.1007/s00125-010-1692-1. Epub 2010 Mar 11. Diabetologia. 2010. PMID: 20221584 Free PMC article.
Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.
da Silva Xavier G, Farhan H, Kim H, Caxaria S, Johnson P, Hughes S, Bugliani M, Marselli L, Marchetti P, Birzele F, Sun G, Scharfmann R, Rutter J, Siniakowicz K, Weir G, Parker H, Reimann F, Gribble FM, Rutter GA. da Silva Xavier G, et al. Among authors: reimann f. Diabetologia. 2011 Apr;54(4):819-27. doi: 10.1007/s00125-010-2010-7. Epub 2010 Dec 23. Diabetologia. 2011. PMID: 21181396 Free PMC article.
PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.
Iglesias J, Barg S, Vallois D, Lahiri S, Roger C, Yessoufou A, Pradevand S, McDonald A, Bonal C, Reimann F, Gribble F, Debril MB, Metzger D, Chambon P, Herrera P, Rutter GA, Prentki M, Thorens B, Wahli W. Iglesias J, et al. Among authors: reimann f. J Clin Invest. 2012 Nov;122(11):4105-17. doi: 10.1172/JCI42127. Epub 2012 Oct 24. J Clin Invest. 2012. PMID: 23093780 Free PMC article.
LKB1 and AMPK differentially regulate pancreatic β-cell identity.
Kone M, Pullen TJ, Sun G, Ibberson M, Martinez-Sanchez A, Sayers S, Nguyen-Tu MS, Kantor C, Swisa A, Dor Y, Gorman T, Ferrer J, Thorens B, Reimann F, Gribble F, McGinty JA, Chen L, French PM, Birzele F, Hildebrandt T, Uphues I, Rutter GA. Kone M, et al. Among authors: reimann f. FASEB J. 2014 Nov;28(11):4972-85. doi: 10.1096/fj.14-257667. Epub 2014 Jul 28. FASEB J. 2014. PMID: 25070369 Free PMC article.
LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia.
Sun G, da Silva Xavier G, Gorman T, Priest C, Solomou A, Hodson DJ, Foretz M, Viollet B, Herrera PL, Parker H, Reimann F, Gribble FM, Migrenne S, Magnan C, Marley A, Rutter GA. Sun G, et al. Among authors: reimann f. Mol Metab. 2015 Jan 31;4(4):277-86. doi: 10.1016/j.molmet.2015.01.006. eCollection 2015 Apr. Mol Metab. 2015. PMID: 25830091 Free PMC article.
340 results