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Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation.
Xia W, Veeragandham P, Cao Y, Xu Y, Rhyne TE, Qian J, Hung CW, Zhao P, Jones Y, Gao H, Liddle C, Yu RT, Downes M, Evans RM, Rydén M, Wabitsch M, Wang Z, Hakozaki H, Schöneberg J, Reilly SM, Huang J, Saltiel AR. Xia W, et al. Among authors: reilly sm. Nat Metab. 2024 Feb;6(2):273-289. doi: 10.1038/s42255-024-00978-0. Epub 2024 Jan 29. Nat Metab. 2024. PMID: 38286821 Free PMC article.
Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling.
Luan D, Dadpey B, Zaid J, Bridge-Comer PE, DeLuca JH, Xia W, Castle J, Reilly SM. Luan D, et al. Among authors: reilly sm. Diabetes. 2023 Mar 1;72(3):367-374. doi: 10.2337/db22-0444. Diabetes. 2023. PMID: 36449000 Free PMC article.
Xanthine oxidase inhibitor urate-lowering therapy titration to target decreases serum free fatty acids in gout and suppresses lipolysis by adipocytes.
Guma M, Dadpey B, Coras R, Mikuls TR, Hamilton B, Quehenberger O, Thorisdottir H, Bittleman D, Lauro K, Reilly SM, Liu-Bryan R, Terkeltaub R. Guma M, et al. Among authors: reilly sm. Arthritis Res Ther. 2022 Jul 25;24(1):175. doi: 10.1186/s13075-022-02852-4. Arthritis Res Ther. 2022. PMID: 35879786 Free PMC article.
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.
Keinan O, Valentine JM, Xiao H, Mahata SK, Reilly SM, Abu-Odeh M, Deluca JH, Dadpey B, Cho L, Pan A, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, Lusis AJ, Laakso M, Chouchani ET, Rydén M, Saltiel AR. Keinan O, et al. Among authors: reilly sm. Nature. 2021 Nov;599(7884):296-301. doi: 10.1038/s41586-021-04019-8. Epub 2021 Oct 27. Nature. 2021. PMID: 34707293 Free PMC article.
116 results