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Depletion and activation of microglia impact metabolic connectivity of the mouse brain.
J Neuroinflammation. 2023 Feb 24;20(1):47. doi: 10.1186/s12974-023-02735-8.
J Neuroinflammation. 2023.
PMID: 36829182
Free PMC article.
Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency.
Reifschneider A, Robinson S, van Lengerich B, Gnörich J, Logan T, Heindl S, Vogt MA, Weidinger E, Riedl L, Wind K, Zatcepin A, Pesämaa I, Haberl S, Nuscher B, Kleinberger G, Klimmt J, Götzl JK, Liesz A, Bürger K, Brendel M, Levin J, Diehl-Schmid J, Suh J, Di Paolo G, Lewcock JW, Monroe KM, Paquet D, Capell A, Haass C.
Reifschneider A, et al.
EMBO J. 2022 Feb 15;41(4):e109108. doi: 10.15252/embj.2021109108. Epub 2022 Jan 12.
EMBO J. 2022.
PMID: 35019161
Free PMC article.
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Toxicity of ionizing radiation (IR) in a human induced pluripotent stem cell (hiPSC)-derived 3D early neurodevelopmental model.
Klatt A, Salzmann E, Schneider LJ, Reifschneider A, Korneck M, Hermle P, Bürkle A, Stoll D, Kadereit S.
Klatt A, et al. Among authors: reifschneider a.
Arch Toxicol. 2019 Oct;93(10):2879-2893. doi: 10.1007/s00204-019-02553-z. Epub 2019 Sep 7.
Arch Toxicol. 2019.
PMID: 31493029
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Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.
Götzl JK, Brendel M, Werner G, Parhizkar S, Sebastian Monasor L, Kleinberger G, Colombo AV, Deussing M, Wagner M, Winkelmann J, Diehl-Schmid J, Levin J, Fellerer K, Reifschneider A, Bultmann S, Bartenstein P, Rominger A, Tahirovic S, Smith ST, Madore C, Butovsky O, Capell A, Haass C.
Götzl JK, et al. Among authors: reifschneider a.
EMBO Mol Med. 2019 Jun;11(6):e9711. doi: 10.15252/emmm.201809711.
EMBO Mol Med. 2019.
PMID: 31122931
Free PMC article.
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Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
Götzl JK, Colombo AV, Fellerer K, Reifschneider A, Werner G, Tahirovic S, Haass C, Capell A.
Götzl JK, et al. Among authors: reifschneider a.
Mol Neurodegener. 2018 Sep 4;13(1):48. doi: 10.1186/s13024-018-0281-5.
Mol Neurodegener. 2018.
PMID: 30180904
Free PMC article.
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The wide genetic landscape of clinical frontotemporal dementia: systematic combined sequencing of 121 consecutive subjects.
Blauwendraat C, Wilke C, Simón-Sánchez J, Jansen IE, Reifschneider A, Capell A, Haass C, Castillo-Lizardo M, Biskup S, Maetzler W, Rizzu P, Heutink P, Synofzik M.
Blauwendraat C, et al. Among authors: reifschneider a.
Genet Med. 2018 Feb;20(2):240-249. doi: 10.1038/gim.2017.102. Epub 2017 Jul 27.
Genet Med. 2018.
PMID: 28749476
Free PMC article.
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