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Page 1
Improving oral bioavailability of cyclic peptides by N-methylation.
Räder AFB, Reichart F, Weinmüller M, Kessler H. Räder AFB, et al. Among authors: reichart f. Bioorg Med Chem. 2018 Jun 1;26(10):2766-2773. doi: 10.1016/j.bmc.2017.08.031. Epub 2017 Aug 31. Bioorg Med Chem. 2018. PMID: 28886995 Free article. Review.
Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway.
Schumacher-Klinger A, Fanous J, Merzbach S, Weinmüller M, Reichart F, Räder AFB, Gitlin-Domagalska A, Gilon C, Kessler H, Hoffman A. Schumacher-Klinger A, et al. Among authors: reichart f. Mol Pharm. 2018 Aug 6;15(8):3468-3477. doi: 10.1021/acs.molpharmaceut.8b00466. Epub 2018 Jul 25. Mol Pharm. 2018. PMID: 29976060
Orally Active Peptides: Is There a Magic Bullet?
Räder AFB, Weinmüller M, Reichart F, Schumacher-Klinger A, Merzbach S, Gilon C, Hoffman A, Kessler H. Räder AFB, et al. Among authors: reichart f. Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14414-14438. doi: 10.1002/anie.201807298. Epub 2018 Oct 3. Angew Chem Int Ed Engl. 2018. PMID: 30144240 Review.
Selective Targeting of Integrin αvβ8 by a Highly Active Cyclic Peptide.
Reichart F, Maltsev OV, Kapp TG, Räder AFB, Weinmüller M, Marelli UK, Notni J, Wurzer A, Beck R, Wester HJ, Steiger K, Di Maro S, Di Leva FS, Marinelli L, Nieberler M, Reuning U, Schwaiger M, Kessler H. Reichart F, et al. J Med Chem. 2019 Feb 28;62(4):2024-2037. doi: 10.1021/acs.jmedchem.8b01588. Epub 2019 Feb 6. J Med Chem. 2019. PMID: 30657681
Novel cilengitide-based cyclic RGD peptides as αvβ3 integrin inhibitors.
Meena CL, Singh D, Weinmüller M, Reichart F, Dangi A, Marelli UK, Zahler S, Sanjayan GJ. Meena CL, et al. Among authors: reichart f. Bioorg Med Chem Lett. 2020 Apr 15;30(8):127039. doi: 10.1016/j.bmcl.2020.127039. Epub 2020 Feb 17. Bioorg Med Chem Lett. 2020. PMID: 32094009
Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3.
Weinmüller M, Rechenmacher F, Kiran Marelli U, Reichart F, Kapp TG, Räder AFB, Di Leva FS, Marinelli L, Novellino E, Muñoz-Félix JM, Hodivala-Dilke K, Schumacher A, Fanous J, Gilon C, Hoffman A, Kessler H. Weinmüller M, et al. Among authors: reichart f. Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16405-16409. doi: 10.1002/anie.201709709. Epub 2017 Nov 23. Angew Chem Int Ed Engl. 2017. PMID: 29072809
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.
Merlino F, Daniele S, La Pietra V, Di Maro S, Di Leva FS, Brancaccio D, Tomassi S, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Reichart F, Cavallini C, Costa B, Piccarducci R, Taliani S, Da Settimo F, Martini C, Kessler H, Novellino E, Marinelli L. Merlino F, et al. Among authors: reichart f. J Med Chem. 2018 Jun 14;61(11):4791-4809. doi: 10.1021/acs.jmedchem.8b00004. Epub 2018 Jun 4. J Med Chem. 2018. PMID: 29775303
Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin.
Han J, Räder AFB, Reichart F, Aikman B, Wenzel MN, Woods B, Weinmüller M, Ludwig BS, Stürup S, Groothuis GMM, Permentier HP, Bischoff R, Kessler H, Horvatovich P, Casini A. Han J, et al. Among authors: reichart f. Bioconjug Chem. 2018 Nov 21;29(11):3856-3865. doi: 10.1021/acs.bioconjchem.8b00682. Epub 2018 Nov 13. Bioconjug Chem. 2018. PMID: 30380298
Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand.
Tomassi S, D'Amore VM, Di Leva FS, Vannini A, Quilici G, Weinmüller M, Reichart F, Amato J, Romano B, Izzo AA, Di Maro S, Novellino E, Musco G, Gianni T, Kessler H, Marinelli L. Tomassi S, et al. Among authors: reichart f. J Med Chem. 2021 May 27;64(10):6972-6984. doi: 10.1021/acs.jmedchem.1c00533. Epub 2021 May 7. J Med Chem. 2021. PMID: 33961417 Free PMC article.
21 results