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Enhanced Immunogenicity of Mitochondrial-Localized Proteins in Cancer Cells.
Prota G, Gileadi U, Rei M, Lechuga-Vieco AV, Chen JL, Galiani S, Bedard M, Lau VWC, Fanchi LF, Artibani M, Hu Z, Gordon S, Rehwinkel J, Enríquez JA, Ahmed AA, Schumacher TN, Cerundolo V. Prota G, et al. Among authors: rehwinkel j. Cancer Immunol Res. 2020 May;8(5):685-697. doi: 10.1158/2326-6066.CIR-19-0467. Epub 2020 Mar 23. Cancer Immunol Res. 2020. PMID: 32205315
Deoxyguanosine is a TLR7 agonist.
Davenne T, Bridgeman A, Rigby RE, Rehwinkel J. Davenne T, et al. Among authors: rehwinkel j. Eur J Immunol. 2020 Jan;50(1):56-62. doi: 10.1002/eji.201948151. Epub 2019 Nov 14. Eur J Immunol. 2020. PMID: 31608988 Free PMC article.
RNA degradation in antiviral immunity and autoimmunity.
Rigby RE, Rehwinkel J. Rigby RE, et al. Among authors: rehwinkel j. Trends Immunol. 2015 Mar;36(3):179-88. doi: 10.1016/j.it.2015.02.001. Epub 2015 Feb 20. Trends Immunol. 2015. PMID: 25709093 Free PMC article. Review.
Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.
Hertzog J, Dias Junior AG, Rigby RE, Donald CL, Mayer A, Sezgin E, Song C, Jin B, Hublitz P, Eggeling C, Kohl A, Rehwinkel J. Hertzog J, et al. Among authors: rehwinkel j. Eur J Immunol. 2018 Jul;48(7):1120-1136. doi: 10.1002/eji.201847483. Epub 2018 Apr 6. Eur J Immunol. 2018. PMID: 29572905 Free PMC article.
Mitochondrial double-stranded RNA triggers antiviral signalling in humans.
Dhir A, Dhir S, Borowski LS, Jimenez L, Teitell M, Rötig A, Crow YJ, Rice GI, Duffy D, Tamby C, Nojima T, Munnich A, Schiff M, de Almeida CR, Rehwinkel J, Dziembowski A, Szczesny RJ, Proudfoot NJ. Dhir A, et al. Among authors: rehwinkel j. Nature. 2018 Aug;560(7717):238-242. doi: 10.1038/s41586-018-0363-0. Epub 2018 Jul 25. Nature. 2018. PMID: 30046113 Free PMC article.
Redox homeostasis maintained by GPX4 facilitates STING activation.
Jia M, Qin D, Zhao C, Chai L, Yu Z, Wang W, Tong L, Lv L, Wang Y, Rehwinkel J, Yu J, Zhao W. Jia M, et al. Among authors: rehwinkel j. Nat Immunol. 2020 Jul;21(7):727-735. doi: 10.1038/s41590-020-0699-0. Epub 2020 Jun 15. Nat Immunol. 2020. PMID: 32541831
Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype.
Fraser E, Denney L, Antanaviciute A, Blirando K, Vuppusetty C, Zheng Y, Repapi E, Iotchkova V, Taylor S, Ashley N, St Noble V, Benamore R, Hoyles R, Clelland C, Rastrick JMD, Hardman CS, Alham NK, Rigby RE, Simmons A, Rehwinkel J, Ho LP. Fraser E, et al. Among authors: rehwinkel j. Front Immunol. 2021 Mar 5;12:623430. doi: 10.3389/fimmu.2021.623430. eCollection 2021. Front Immunol. 2021. PMID: 33746960 Free PMC article.
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