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Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1.
Beck EM, Parnell E, Cowley A, Porter A, Gillespie J, Robinson J, Robinson L, Pannifer AD, Hamon V, Jones P, Morrison A, McElroy S, Timmerman M, Rutjes H, Mahajan P, Wiejak J, Luchowska-Stańska U, Morgan D, Barker G, Rehmann H, Yarwood SJ. Beck EM, et al. Among authors: rehmann h. Cells. 2019 Nov 12;8(11):1425. doi: 10.3390/cells8111425. Cells. 2019. PMID: 31726720 Free PMC article.
Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.
Gloerich M, Ponsioen B, Vliem MJ, Zhang Z, Zhao J, Kooistra MR, Price LS, Ritsma L, Zwartkruis FJ, Rehmann H, Jalink K, Bos JL. Gloerich M, et al. Among authors: rehmann h. Mol Cell Biol. 2010 Nov;30(22):5421-31. doi: 10.1128/MCB.00463-10. Epub 2010 Sep 20. Mol Cell Biol. 2010. PMID: 20855527 Free PMC article.
Structural dynamics in the activation of Epac.
Harper SM, Wienk H, Wechselberger RW, Bos JL, Boelens R, Rehmann H. Harper SM, et al. Among authors: rehmann h. J Biol Chem. 2008 Mar 7;283(10):6501-8. doi: 10.1074/jbc.M707849200. Epub 2007 Dec 31. J Biol Chem. 2008. PMID: 18167352 Free article.
Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control.
Pannekoek WJ, van Dijk JJ, Chan OY, Huveneers S, Linnemann JR, Spanjaard E, Brouwer PM, van der Meer AJ, Zwartkruis FJ, Rehmann H, de Rooij J, Bos JL. Pannekoek WJ, et al. Among authors: rehmann h. Cell Signal. 2011 Dec;23(12):2056-64. doi: 10.1016/j.cellsig.2011.07.022. Epub 2011 Aug 4. Cell Signal. 2011. PMID: 21840392
Epac-inhibitors: facts and artefacts.
Rehmann H. Rehmann H. Sci Rep. 2013 Oct 23;3:3032. doi: 10.1038/srep03032. Sci Rep. 2013. PMID: 24149987 Free PMC article.
78 results