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Melanoma 2.0. Skin cancer as a paradigm for emerging diagnostic technologies, computational modelling and artificial intelligence.
Vera J, Lai X, Baur A, Erdmann M, Gupta S, Guttà C, Heinzerling L, Heppt MV, Kazmierczak PM, Kunz M, Lischer C, Pützer BM, Rehm M, Ostalecki C, Retzlaff J, Witt S, Wolkenhauer O, Berking C. Vera J, et al. Among authors: rehm m. Brief Bioinform. 2022 Nov 19;23(6):bbac433. doi: 10.1093/bib/bbac433. Brief Bioinform. 2022. PMID: 36252807 Review.
Whither systems medicine?
Apweiler R, Beissbarth T, Berthold MR, Blüthgen N, Burmeister Y, Dammann O, Deutsch A, Feuerhake F, Franke A, Hasenauer J, Hoffmann S, Höfer T, Jansen PL, Kaderali L, Klingmüller U, Koch I, Kohlbacher O, Kuepfer L, Lammert F, Maier D, Pfeifer N, Radde N, Rehm M, Roeder I, Saez-Rodriguez J, Sax U, Schmeck B, Schuppert A, Seilheimer B, Theis FJ, Vera J, Wolkenhauer O. Apweiler R, et al. Among authors: rehm m. Exp Mol Med. 2018 Mar 2;50(3):e453. doi: 10.1038/emm.2017.290. Exp Mol Med. 2018. PMID: 29497170 Free PMC article. Review.
Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma.
Rožanc J, Sakellaropoulos T, Antoranz A, Guttà C, Podder B, Vetma V, Rufo N, Agostinis P, Pliaka V, Sauter T, Kulms D, Rehm M, Alexopoulos LG. Rožanc J, et al. Among authors: rehm m. Cell Death Differ. 2019 Aug;26(8):1365-1378. doi: 10.1038/s41418-018-0210-8. Epub 2018 Oct 15. Cell Death Differ. 2019. PMID: 30323272 Free PMC article.
Low expression of pro-apoptotic proteins Bax, Bak and Smac indicates prolonged progression-free survival in chemotherapy-treated metastatic melanoma.
Guttà C, Rahman A, Aura C, Dynoodt P, Charles EM, Hirschenhahn E, Joseph J, Wouters J, de Chaumont C, Rafferty M, Warren M, van den Oord JJ, Gallagher WM, Rehm M. Guttà C, et al. Among authors: rehm m. Cell Death Dis. 2020 Feb 13;11(2):124. doi: 10.1038/s41419-020-2309-3. Cell Death Dis. 2020. PMID: 32054850 Free PMC article.
294 results