Reggio PH - Search Results

1

Pregnenolone can protect the brain from cannabis intoxication.

Vallée M, Vitiello S, Bellocchio L, Hébert-Chatelain E, Monlezun S, Martin-Garcia E, Kasanetz F, Baillie GL, Panin F, Cathala A, Roullot-Lacarrière V, Fabre S, Hurst DP, Lynch DL, Shore DM, Deroche-Gamonet V, Spampinato U, Revest JM, Maldonado R, Reggio PH, Ross RA, Marsicano G, Piazza PV. Vallée M, et al. Among authors: reggio ph. Science. 2014 Jan 3;343(6166):94-8. doi: 10.1126/science.1243985. Science. 2014. PMID: 24385629 Free PMC article.

2

Conformational memories and the endocannabinoid binding site at the cannabinoid CB1 receptor.

Barnett-Norris J, Hurst DP, Lynch DL, Guarnieri F, Makriyannis A, Reggio PH. Barnett-Norris J, et al. Among authors: reggio ph. J Med Chem. 2002 Aug 15;45(17):3649-59. doi: 10.1021/jm0200761. J Med Chem. 2002. PMID: 12166938

3

N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) interaction with LYS 3.28(192) is crucial for its inverse agonism at the cannabinoid CB1 receptor.

Hurst DP, Lynch DL, Barnett-Norris J, Hyatt SM, Seltzman HH, Zhong M, Song ZH, Nie J, Lewis D, Reggio PH. Hurst DP, et al. Among authors: reggio ph. Mol Pharmacol. 2002 Dec;62(6):1274-87. doi: 10.1124/mol.62.6.1274. Mol Pharmacol. 2002. PMID: 12435794

4

Activation of the cannabinoid CB1 receptor may involve a W6 48/F3 36 rotamer toggle switch.

Singh R, Hurst DP, Barnett-Norris J, Lynch DL, Reggio PH, Guarnieri F. Singh R, et al. Among authors: reggio ph. J Pept Res. 2002 Dec;60(6):357-70. doi: 10.1034/j.1399-3011.2002.21065.x. J Pept Res. 2002. PMID: 12464114

5

An aromatic microdomain at the cannabinoid CB(1) receptor constitutes an agonist/inverse agonist binding region.

McAllister SD, Rizvi G, Anavi-Goffer S, Hurst DP, Barnett-Norris J, Lynch DL, Reggio PH, Abood ME. McAllister SD, et al. Among authors: reggio ph. J Med Chem. 2003 Nov 20;46(24):5139-52. doi: 10.1021/jm0302647. J Med Chem. 2003. PMID: 14613317

6

Structural mimicry in class A G protein-coupled receptor rotamer toggle switches: the importance of the F3.36(201)/W6.48(357) interaction in cannabinoid CB1 receptor activation.

McAllister SD, Hurst DP, Barnett-Norris J, Lynch D, Reggio PH, Abood ME. McAllister SD, et al. Among authors: reggio ph. J Biol Chem. 2004 Nov 12;279(46):48024-37. doi: 10.1074/jbc.M406648200. Epub 2004 Aug 23. J Biol Chem. 2004. PMID: 15326174 Free article.

7

Cysteine 2.59(89) in the second transmembrane domain of human CB2 receptor is accessible within the ligand binding crevice: evidence for possible CB2 deviation from a rhodopsin template.

Zhang R, Hurst DP, Barnett-Norris J, Reggio PH, Song ZH. Zhang R, et al. Among authors: reggio ph. Mol Pharmacol. 2005 Jul;68(1):69-83. doi: 10.1124/mol.104.007823. Epub 2005 Apr 19. Mol Pharmacol. 2005. PMID: 15840841

8

Lipids, lipid rafts and caveolae: their importance for GPCR signaling and their centrality to the endocannabinoid system.

Barnett-Norris J, Lynch D, Reggio PH. Barnett-Norris J, et al. Among authors: reggio ph. Life Sci. 2005 Aug 19;77(14):1625-39. doi: 10.1016/j.lfs.2005.05.040. Life Sci. 2005. PMID: 15993425 Review.

9

Adamantyl cannabinoids: a novel class of cannabinergic ligands.

Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, Hurst DP, Reggio PH, Deschamps JR, Parrish DA, George C, Järbe TU, Lamb RJ, Makriyannis A. Lu D, et al. Among authors: reggio ph. J Med Chem. 2005 Jul 14;48(14):4576-85. doi: 10.1021/jm058175c. J Med Chem. 2005. PMID: 15999995

10

Molecular dynamics simulations of the endocannabinoid N-arachidonoylethanolamine (anandamide) in a phospholipid bilayer: probing structure and dynamics.

Lynch DL, Reggio PH. Lynch DL, et al. Among authors: reggio ph. J Med Chem. 2005 Jul 28;48(15):4824-33. doi: 10.1021/jm058185d. J Med Chem. 2005. PMID: 16033262

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