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A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target.
Debnath A, Parsonage D, Andrade RM, He C, Cobo ER, Hirata K, Chen S, García-Rivera G, Orozco E, Martínez MB, Gunatilleke SS, Barrios AM, Arkin MR, Poole LB, McKerrow JH, Reed SL. Debnath A, et al. Among authors: reed sl. Nat Med. 2012 Jun;18(6):956-60. doi: 10.1038/nm.2758. Nat Med. 2012. PMID: 22610278 Free PMC article.
Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.
Debnath A, Shahinas D, Bryant C, Hirata K, Miyamoto Y, Hwang G, Gut J, Renslo AR, Pillai DR, Eckmann L, Reed SL, McKerrow JH. Debnath A, et al. Among authors: reed sl. Antimicrob Agents Chemother. 2014 Jul;58(7):4138-44. doi: 10.1128/AAC.02576-14. Epub 2014 May 12. Antimicrob Agents Chemother. 2014. PMID: 24820073 Free PMC article.
Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent.
Capparelli EV, Bricker-Ford R, Rogers MJ, McKerrow JH, Reed SL. Capparelli EV, et al. Among authors: reed sl. Antimicrob Agents Chemother. 2016 Dec 27;61(1):e01947-16. doi: 10.1128/AAC.01947-16. Print 2017 Jan. Antimicrob Agents Chemother. 2016. PMID: 27821451 Free PMC article. Clinical Trial.
Cysteine proteases in protozoan parasites.
Siqueira-Neto JL, Debnath A, McCall LI, Bernatchez JA, Ndao M, Reed SL, Rosenthal PJ. Siqueira-Neto JL, et al. Among authors: reed sl. PLoS Negl Trop Dis. 2018 Aug 23;12(8):e0006512. doi: 10.1371/journal.pntd.0006512. eCollection 2018 Aug. PLoS Negl Trop Dis. 2018. PMID: 30138453 Free PMC article. Review.
125 results