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USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin.
Ji L, Lu B, Zamponi R, Charlat O, Aversa R, Yang Z, Sigoillot F, Zhu X, Hu T, Reece-Hoyes JS, Russ C, Michaud G, Tchorz JS, Jiang X, Cong F. Ji L, et al. Among authors: reece hoyes js. Nat Commun. 2019 Sep 13;10(1):4184. doi: 10.1038/s41467-019-12143-3. Nat Commun. 2019. PMID: 31519875 Free PMC article.
Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites.
Paul A, Annunziato S, Lu B, Sun T, Evrova O, Planas-Paz L, Orsini V, Terracciano LM, Charlat O, Loureiro ZY, Ji L, Zamponi R, Sigoillot F, Lei H, Lindeman A, Russ C, Reece-Hoyes JS, Nicholson TB, Tchorz JS, Cong F. Paul A, et al. Among authors: reece hoyes js. Nat Commun. 2022 Feb 17;13(1):930. doi: 10.1038/s41467-022-28567-3. Nat Commun. 2022. PMID: 35177623 Free PMC article.
YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury.
Planas-Paz L, Sun T, Pikiolek M, Cochran NR, Bergling S, Orsini V, Yang Z, Sigoillot F, Jetzer J, Syed M, Neri M, Schuierer S, Morelli L, Hoppe PS, Schwarzer W, Cobos CM, Alford JL, Zhang L, Cuttat R, Waldt A, Carballido-Perrig N, Nigsch F, Kinzel B, Nicholson TB, Yang Y, Mao X, Terracciano LM, Russ C, Reece-Hoyes JS, Gubser Keller C, Sailer AW, Bouwmeester T, Greenbaum LE, Lugus JJ, Cong F, McAllister G, Hoffman GR, Roma G, Tchorz JS. Planas-Paz L, et al. Among authors: reece hoyes js. Cell Stem Cell. 2019 Jul 3;25(1):39-53.e10. doi: 10.1016/j.stem.2019.04.005. Epub 2019 May 9. Cell Stem Cell. 2019. PMID: 31080135 Free article.
Tankyrase Inhibitor Sensitizes Lung Cancer Cells to Endothelial Growth Factor Receptor (EGFR) Inhibition via Stabilizing Angiomotins and Inhibiting YAP Signaling.
Wang H, Lu B, Castillo J, Zhang Y, Yang Z, McAllister G, Lindeman A, Reece-Hoyes J, Tallarico J, Russ C, Hoffman G, Xu W, Schirle M, Cong F. Wang H, et al. J Biol Chem. 2016 Jul 15;291(29):15256-66. doi: 10.1074/jbc.M116.722967. Epub 2016 May 26. J Biol Chem. 2016. PMID: 27231341 Free PMC article.
IRF2 is a master regulator of human keratinocyte stem cell fate.
Mercado N, Schutzius G, Kolter C, Estoppey D, Bergling S, Roma G, Gubser Keller C, Nigsch F, Salathe A, Terranova R, Reece-Hoyes J, Alford J, Russ C, Knehr J, Hoepfner D, Aebi A, Ruffner H, Beck TC, Jagannathan S, Olson CM, Sheppard HE, Elsarrag SZ, Bouwmeester T, Frederiksen M, Lohmann F, Lin CY, Kirkland S. Mercado N, et al. Nat Commun. 2019 Oct 14;10(1):4676. doi: 10.1038/s41467-019-12559-x. Nat Commun. 2019. PMID: 31611556 Free PMC article.
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, Rodríguez-Molina JB, Miller HR, Brittain SM, Murphy J, Zambrowski M, Boynton G, Wang Y, Chen A, Molind GJ, Wilbertz JH, Artus-Revel CG, Jia M, Akinjiyan FA, Turner J, Knehr J, Carbone W, Schuierer S, Reece-Hoyes JS, Xie K, Saran C, Williams ET, Roma G, Spencer M, Jenkins J, George EL, Thomas JR, Michaud G, Schirle M, Tallarico J, Passmore LA, Chao JA, Beckwith REJ. Ross NT, et al. Among authors: reece hoyes js. Nat Chem Biol. 2020 Jan;16(1):50-59. doi: 10.1038/s41589-019-0424-1. Epub 2019 Dec 9. Nat Chem Biol. 2020. PMID: 31819276 Free PMC article.
Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, Rodríguez-Molina JB, Miller HR, Brittain SM, Murphy J, Zambrowski M, Boynton G, Wang Y, Chen A, Molind GJ, Wilbertz JH, Artus-Revel CG, Jia M, Akinjiyan FA, Turner J, Knehr J, Carbone W, Schuierer S, Reece-Hoyes JS, Xie K, Saran C, Williams ET, Roma G, Spencer M, Jenkins J, George EL, Thomas JR, Michaud G, Schirle M, Tallarico J, Passmore LA, Chao JA, Beckwith REJ. Ross NT, et al. Among authors: reece hoyes js. Nat Chem Biol. 2020 Apr;16(4):479. doi: 10.1038/s41589-020-0508-y. Nat Chem Biol. 2020. PMID: 32139909
67 results