Redmond JM - Search Results

1

A cancer-associated, genome protective programme engaging PKCε.

Parker PJ, Lockwood N, Davis K, Kelly JR, Soliman TN, Pardo AL, Marshall JJT, Redmond JM, Vitale M, Silvia Martini. Parker PJ, et al. Among authors: redmond jm. Adv Biol Regul. 2020 Dec;78:100759. doi: 10.1016/j.jbior.2020.100759. Epub 2020 Oct 7. Adv Biol Regul. 2020. PMID: 33039823 Free PMC article. Review.

2

Discovery of 3-Oxabicyclo[4.1.0]heptane, a Non-nitrogen Containing Morpholine Isostere, and Its Application in Novel Inhibitors of the PI3K-AKT-mTOR Pathway.

Hobbs H, Bravi G, Campbell I, Convery M, Davies H, Inglis G, Pal S, Peace S, Redmond J, Summers D. Hobbs H, et al. J Med Chem. 2019 Aug 8;62(15):6972-6984. doi: 10.1021/acs.jmedchem.9b00348. Epub 2019 Jul 23. J Med Chem. 2019. PMID: 31283227

3

Correction to Discovery of 3-Oxabicyclo[4.1.0]heptane, a Non-nitrogen Containing Morpholine Isostere, and Its Application in Novel Inhibitors of the PI3K-AKT-mTOR Pathway.

Hobbs H, Bravi G, Campbell I, Convery M, Davies H, Inglis G, Pal S, Peace S, Redmond J, Summers D. Hobbs H, et al. J Med Chem. 2019 Oct 10;62(19):8880. doi: 10.1021/acs.jmedchem.9b01498. Epub 2019 Sep 25. J Med Chem. 2019. PMID: 31553183 No abstract available.

4

Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs.

Shah RR, Redmond JM, Mihut A, Menon M, Evans JP, Murphy JA, Bartholomew MA, Coe DM. Shah RR, et al. Among authors: redmond jm. Bioorg Med Chem. 2020 Mar 1;28(5):115326. doi: 10.1016/j.bmc.2020.115326. Epub 2020 Jan 23. Bioorg Med Chem. 2020. PMID: 32001089 Free article.

5

Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs.

Ayre J, Redmond JM, Vitulli G, Tomlinson L, Weaver R, Comeo E, Bosquillon C, Stocks MJ. Ayre J, et al. Among authors: redmond jm. J Med Chem. 2022 Jul 28;65(14):9802-9818. doi: 10.1021/acs.jmedchem.2c00416. Epub 2022 Jul 7. J Med Chem. 2022. PMID: 35798565 Free PMC article.

6

Modular Construction of Fluoroarenes from a New Difluorinated Building Block by Cross-Coupling/Electrocyclisation/Dehydrofluorination Reactions.

Percy JM, Emerson H, Fyfe JW, Kennedy AR, Maciuk S, Orr D, Rathouská L, Redmond JM, Wilson PG. Percy JM, et al. Among authors: redmond jm. Chemistry. 2016 Aug 16;22(34):12166-75. doi: 10.1002/chem.201601584. Epub 2016 Jul 14. Chemistry. 2016. PMID: 27415819 Free article.

7

Speciation control during Suzuki-Miyaura cross-coupling of haloaryl and haloalkenyl MIDA boronic esters.

Fyfe JW, Valverde E, Seath CP, Kennedy AR, Redmond JM, Anderson NA, Watson AJ. Fyfe JW, et al. Among authors: redmond jm. Chemistry. 2015 Jun 8;21(24):8951-64. doi: 10.1002/chem.201500970. Epub 2015 May 8. Chemistry. 2015. PMID: 25959852 Free article.

8

Synthesis of functionalised 4H-quinolizin-4-ones via tandem Horner-Wadsworth-Emmons olefination/cyclisation.

Muir CW, Kennedy AR, Redmond JM, Watson AJ. Muir CW, et al. Among authors: redmond jm. Org Biomol Chem. 2013 May 28;11(20):3337-40. doi: 10.1039/c3ob40578h. Org Biomol Chem. 2013. PMID: 23558690 Free article.

9

Suzuki-Miyaura coupling reactions of iodo(difluoroenol) derivatives, fluorinated building blocks accessible at near-ambient temperatures.

Wilson PG, Percy JM, Redmond JM, McCarter AW. Wilson PG, et al. Among authors: redmond jm. J Org Chem. 2012 Aug 3;77(15):6384-93. doi: 10.1021/jo3011705. Epub 2012 Jul 17. J Org Chem. 2012. PMID: 22769401

10

Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase.

Guzman JD, Pesnot T, Barrera DA, Davies HM, McMahon E, Evangelopoulos D, Mortazavi PN, Munshi T, Maitra A, Lamming ED, Angell R, Gershater MC, Redmond JM, Needham D, Ward JM, Cuca LE, Hailes HC, Bhakta S. Guzman JD, et al. Among authors: redmond jm. J Antimicrob Chemother. 2015;70(6):1691-703. doi: 10.1093/jac/dkv010. Epub 2015 Feb 4. J Antimicrob Chemother. 2015. PMID: 25656411 Free PMC article.

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