Reddy T - Search Results

1

Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity.

Kadur Lakshminarasimha Murthy P, Xi R, Arguijo D, Everitt JI, Kocak DD, Kobayashi Y, Bozec A, Vicent S, Ding S, Crawford GE, Hsu D, Tata PR, Reddy T, Shen X. Kadur Lakshminarasimha Murthy P, et al. Among authors: reddy t. Dev Cell. 2022 Feb 7;57(3):310-328.e9. doi: 10.1016/j.devcel.2022.01.006. Dev Cell. 2022. PMID: 35134344 Free PMC article.

2

The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes.

Reddy TE, Gertz J, Crawford GE, Garabedian MJ, Myers RM. Reddy TE, et al. Mol Cell Biol. 2012 Sep;32(18):3756-67. doi: 10.1128/MCB.00062-12. Epub 2012 Jul 16. Mol Cell Biol. 2012. PMID: 22801371 Free PMC article.

3

RNA-guided gene activation by CRISPR-Cas9-based transcription factors.

Perez-Pinera P, Kocak DD, Vockley CM, Adler AF, Kabadi AM, Polstein LR, Thakore PI, Glass KA, Ousterout DG, Leong KW, Guilak F, Crawford GE, Reddy TE, Gersbach CA. Perez-Pinera P, et al. Nat Methods. 2013 Oct;10(10):973-6. doi: 10.1038/nmeth.2600. Epub 2013 Jul 25. Nat Methods. 2013. PMID: 23892895 Free PMC article.

4

Distinct properties of cell-type-specific and shared transcription factor binding sites.

Gertz J, Savic D, Varley KE, Partridge EC, Safi A, Jain P, Cooper GM, Reddy TE, Crawford GE, Myers RM. Gertz J, et al. Mol Cell. 2013 Oct 10;52(1):25-36. doi: 10.1016/j.molcel.2013.08.037. Epub 2013 Sep 26. Mol Cell. 2013. PMID: 24076218 Free PMC article.

5

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.

Hilton IB, D'Ippolito AM, Vockley CM, Thakore PI, Crawford GE, Reddy TE, Gersbach CA. Hilton IB, et al. Nat Biotechnol. 2015 May;33(5):510-7. doi: 10.1038/nbt.3199. Epub 2015 Apr 6. Nat Biotechnol. 2015. PMID: 25849900 Free PMC article.

6

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators.

Polstein LR, Perez-Pinera P, Kocak DD, Vockley CM, Bledsoe P, Song L, Safi A, Crawford GE, Reddy TE, Gersbach CA. Polstein LR, et al. Genome Res. 2015 Aug;25(8):1158-69. doi: 10.1101/gr.179044.114. Epub 2015 May 29. Genome Res. 2015. PMID: 26025803 Free PMC article.

7

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.

Thakore PI, D'Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy TE, Crawford GE, Gersbach CA. Thakore PI, et al. Nat Methods. 2015 Dec;12(12):1143-9. doi: 10.1038/nmeth.3630. Epub 2015 Oct 26. Nat Methods. 2015. PMID: 26501517 Free PMC article.

8

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome.

Vockley CM, D'Ippolito AM, McDowell IC, Majoros WH, Safi A, Song L, Crawford GE, Reddy TE. Vockley CM, et al. Cell. 2016 Aug 25;166(5):1269-1281.e19. doi: 10.1016/j.cell.2016.07.049. Cell. 2016. PMID: 27565349 Free PMC article.

9

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.

Klann TS, Black JB, Chellappan M, Safi A, Song L, Hilton IB, Crawford GE, Reddy TE, Gersbach CA. Klann TS, et al. Nat Biotechnol. 2017 Jun;35(6):561-568. doi: 10.1038/nbt.3853. Epub 2017 Apr 3. Nat Biotechnol. 2017. PMID: 28369033 Free PMC article.

10

Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing.

Klann TS, Crawford GE, Reddy TE, Gersbach CA. Klann TS, et al. Methods Mol Biol. 2018;1767:447-480. doi: 10.1007/978-1-4939-7774-1_25. Methods Mol Biol. 2018. PMID: 29524151

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