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Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment.
Schwabkey ZI, Wiesnoski DH, Chang CC, Tsai WB, Pham D, Ahmed SS, Hayase T, Ortega Turrubiates MR, El-Himri RK, Sanchez CA, Hayase E, Frenk Oquendo AC, Miyama T, Halsey TM, Heckel BE, Brown AN, Jin Y, Raybaud M, Prasad R, Flores I, McDaniel L, Chapa V, Lorenzi PL, Warmoes MO, Tan L, Swennes AG, Fowler S, Conner M, McHugh K, Graf T, Jensen VB, Peterson CB, Do KA, Zhang L, Shi Y, Wang Y, Galloway-Pena JR, Okhuysen PC, Daniel-MacDougall CR, Shono Y, Burgos da Silva M, Peled JU, van den Brink MRM, Ajami N, Wargo JA, Reddy P, Valdivia RH, Davey L, Rondon G, Srour SA, Mehta RS, Alousi AM, Shpall EJ, Champlin RE, Shelburne SA, Molldrem JJ, Jamal MA, Karmouch JL, Jenq RR. Schwabkey ZI, et al. Among authors: reddy p. Sci Transl Med. 2022 Nov 16;14(671):eabo3445. doi: 10.1126/scitranslmed.abo3445. Epub 2022 Nov 16. Sci Transl Med. 2022. PMID: 36383683 Free PMC article.
Role of cytokines in the pathophysiology of acute graft-versus-host disease (GVHD): are serum/plasma cytokines potential biomarkers for diagnosis of acute GVHD following allogeneic hematopoietic cell transplantation (Allo-HCT)?
Toubai T, Tanaka J, Paczesny S, Shono Y, Reddy P, Imamura M. Toubai T, et al. Among authors: reddy p. Curr Stem Cell Res Ther. 2012 May;7(3):229-39. doi: 10.2174/157488812799859856. Curr Stem Cell Res Ther. 2012. PMID: 22023620 Review.
Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease.
Mathewson ND, Jenq R, Mathew AV, Koenigsknecht M, Hanash A, Toubai T, Oravecz-Wilson K, Wu SR, Sun Y, Rossi C, Fujiwara H, Byun J, Shono Y, Lindemans C, Calafiore M, Schmidt TM, Honda K, Young VB, Pennathur S, van den Brink M, Reddy P. Mathewson ND, et al. Among authors: reddy p. Nat Immunol. 2016 May;17(5):505-513. doi: 10.1038/ni.3400. Epub 2016 Mar 21. Nat Immunol. 2016. PMID: 26998764 Free PMC article.
B-cell activating factor (BAFF) plasma level at the time of chronic GvHD diagnosis is a potential predictor of non-relapse mortality.
Saliba RM, Sarantopoulos S, Kitko CL, Pawarode A, Goldstein SC, Magenau J, Alousi AM, Churay T, Justman H, Paczesny S, Reddy P, Couriel DR. Saliba RM, et al. Among authors: reddy p. Bone Marrow Transplant. 2017 Jul;52(7):1010-1015. doi: 10.1038/bmt.2017.73. Epub 2017 May 8. Bone Marrow Transplant. 2017. PMID: 28481353 Free PMC article. Clinical Trial.
The Microbiome and Hematopoietic Cell Transplantation: Past, Present, and Future.
Andermann TM, Peled JU, Ho C, Reddy P, Riches M, Storb R, Teshima T, van den Brink MRM, Alousi A, Balderman S, Chiusolo P, Clark WB, Holler E, Howard A, Kean LS, Koh AY, McCarthy PL, McCarty JM, Mohty M, Nakamura R, Rezvani K, Segal BH, Shaw BE, Shpall EJ, Sung AD, Weber D, Whangbo J, Wingard JR, Wood WA, Perales MA, Jenq RR, Bhatt AS; Blood and Marrow Transplant Clinical Trials Network. Andermann TM, et al. Among authors: reddy p. Biol Blood Marrow Transplant. 2018 Jul;24(7):1322-1340. doi: 10.1016/j.bbmt.2018.02.009. Epub 2018 Feb 19. Biol Blood Marrow Transplant. 2018. PMID: 29471034 Free PMC article. Review. No abstract available.
Survival signal REG3α prevents crypt apoptosis to control acute gastrointestinal graft-versus-host disease.
Zhao D, Kim YH, Jeong S, Greenson JK, Chaudhry MS, Hoepting M, Anderson ER, van den Brink MR, Peled JU, Gomes AL, Slingerland AE, Donovan MJ, Harris AC, Levine JE, Ozbek U, Hooper LV, Stappenbeck TS, Ver Heul A, Liu TC, Reddy P, Ferrara JL. Zhao D, et al. Among authors: reddy p. J Clin Invest. 2018 Nov 1;128(11):4970-4979. doi: 10.1172/JCI99261. Epub 2018 Sep 24. J Clin Invest. 2018. PMID: 30106382 Free PMC article. Clinical Trial.
Microbial metabolite sensor GPR43 controls severity of experimental GVHD.
Fujiwara H, Docampo MD, Riwes M, Peltier D, Toubai T, Henig I, Wu SJ, Kim S, Taylor A, Brabbs S, Liu C, Zajac C, Oravecz-Wilson K, Sun Y, Núñez G, Levine JE, van den Brink MRM, Ferrara JLM, Reddy P. Fujiwara H, et al. Among authors: reddy p. Nat Commun. 2018 Sep 10;9(1):3674. doi: 10.1038/s41467-018-06048-w. Nat Commun. 2018. PMID: 30201970 Free PMC article.
Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation.
Seike K, Kiledal A, Fujiwara H, Henig I, Burgos da Silva M, van den Brink MRM, Hein R, Hoostal M, Liu C, Oravecz-Wilson K, Lauder E, Li L, Sun Y, Schmidt TM, Shah YM, Jenq RR, Dick G, Reddy P. Seike K, et al. Among authors: reddy p. Immunity. 2023 Feb 14;56(2):353-368.e6. doi: 10.1016/j.immuni.2023.01.007. Epub 2023 Feb 2. Immunity. 2023. PMID: 36736321 Free PMC article.
Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease.
Lindner S, Miltiadous O, Ramos RJF, Paredes J, Kousa AI, Dai A, Fei T, Lauder E, Frame J, Waters NR, Sadeghi K, Armijo GK, Ghale R, Victor K, Gipson B, Monette S, Russo MV, Nguyen CL, Slingerland J, Taur Y, Markey KA, Andrlova H, Giralt S, Perales MA, Reddy P, Peled JU, Smith M, Cross JR, Burgos da Silva M, Campbell C, van den Brink MRM. Lindner S, et al. Among authors: reddy p. Nat Microbiol. 2024 Mar;9(3):614-630. doi: 10.1038/s41564-024-01617-w. Epub 2024 Mar 1. Nat Microbiol. 2024. PMID: 38429422
3,593 results