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Enantioselective synthesis of 4-amino-3,4-dihydrocoumarins and their non-cyclic hydroxyester precursors: Biological evaluation for the treatment of glioblastoma multiforme.
Borrego LG, Recio R, Moreno N, Chelouan A, Álvarez E, Sánchez-Coronilla A, Caro C, Pearson JR, García-Martín ML, Khiar N, Fernández I. Borrego LG, et al. Among authors: recio r. Eur J Med Chem. 2022 Dec 5;243:114730. doi: 10.1016/j.ejmech.2022.114730. Epub 2022 Sep 1. Eur J Med Chem. 2022. PMID: 36088758 Free article.
Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification.
Recio R, Vengut-Climent E, Mouillac B, Orcel H, López-Lázaro M, Calderón-Montaño JM, Álvarez E, Khiar N, Fernández I. Recio R, et al. Eur J Med Chem. 2017 Sep 29;138:644-660. doi: 10.1016/j.ejmech.2017.06.056. Epub 2017 Jun 28. Eur J Med Chem. 2017. PMID: 28710964
Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity.
Recio R, Lerena P, Pozo E, Calderón-Montaño JM, Burgos-Morón E, López-Lázaro M, Valdivia V, Pernia Leal M, Mouillac B, Organero JÁ, Khiar N, Fernández I. Recio R, et al. J Med Chem. 2021 Jul 22;64(14):10350-10370. doi: 10.1021/acs.jmedchem.1c00793. Epub 2021 Jul 8. J Med Chem. 2021. PMID: 34236855 Free PMC article.
68 results