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Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency.
Jauch AJ, Bignucolo O, Seki S, Ghraichy M, Delmonte OM, von Niederhäusern V, Higgins R, Ghosh A, Nishizawa M, Tanaka M, Baldrich A, Köppen J, Hirsiger JR, Hupfer R, Ehl S, Rensing-Ehl A, Hopfer H, Prince SS, Daley SR, Marquardsen FA, Meyer BJ, Tamm M, Daikeler TD, Diesch T, Kühne T, Helbling A, Berkemeier C, Heijnen I, Navarini AA, Trück J, de Villartay JP, Oxenius A, Berger CT, Hess C, Notarangelo LD, Yamamoto H, Recher M. Jauch AJ, et al. Among authors: recher m. J Allergy Clin Immunol. 2023 Aug;152(2):500-516. doi: 10.1016/j.jaci.2023.03.022. Epub 2023 Mar 31. J Allergy Clin Immunol. 2023. PMID: 37004747 Free PMC article.
Deliberate removal of T cell help improves virus-neutralizing antibody production.
Recher M, Lang KS, Hunziker L, Freigang S, Eschli B, Harris NL, Navarini A, Senn BM, Fink K, Lötscher M, Hangartner L, Zellweger R, Hersberger M, Theocharides A, Hengartner H, Zinkernagel RM. Recher M, et al. Nat Immunol. 2004 Sep;5(9):934-42. doi: 10.1038/ni1102. Epub 2004 Aug 8. Nat Immunol. 2004. PMID: 15300247
Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling.
Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, Heikenwalder M, Harris NL, Junt T, Odermatt B, Clavien PA, Pircher H, Akira S, Hengartner H, Zinkernagel RM. Lang KS, et al. Among authors: recher m. J Clin Invest. 2006 Sep;116(9):2456-63. doi: 10.1172/JCI28349. J Clin Invest. 2006. PMID: 16955143 Free PMC article.
Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia.
de la Fuente MA, Recher M, Rider NL, Strauss KA, Morton DH, Adair M, Bonilla FA, Ochs HD, Gelfand EW, Pessach IM, Walter JE, King A, Giliani S, Pai SY, Notarangelo LD. de la Fuente MA, et al. Among authors: recher m. J Allergy Clin Immunol. 2011 Jul;128(1):139-146. doi: 10.1016/j.jaci.2011.03.042. Epub 2011 May 13. J Allergy Clin Immunol. 2011. PMID: 21570718 Free PMC article.
174 results