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Page 1
Preparation of kinase-biased compounds in the search for lead inhibitors of kinase targets.
Lai JY, Langston S, Adams R, Beevers RE, Boyce R, Burckhardt S, Cobb J, Ferguson Y, Figueroa E, Grimster N, Henry AH, Khan N, Jenkins K, Jones MW, Judkins R, Major J, Masood A, Nally J, Payne H, Payne L, Raphy G, Raynham T, Reader J, Reader V, Reid A, Ruprah P, Shaw M, Sore H, Stirling M, Talbot A, Taylor J, Thompson S, Wada H, Walker D. Lai JY, et al. Among authors: reader v. Med Res Rev. 2005 May;25(3):310-30. doi: 10.1002/med.20026. Med Res Rev. 2005. PMID: 15593285 Review.
Benzimidazole derivatives as arginine mimetics in 1,4-benzodiazepine nonpeptide vitronectin receptor (alpha v beta 3) antagonists.
Keenan RM, Miller WH, Lago MA, Ali FE, Bondinell WE, Callahan JF, Calvo RR, Cousins RD, Hwang SM, Jakas DR, Ku TW, Kwon C, Nguyen TT, Reader VA, Rieman DJ, Ross ST, Takata DT, Uzinskas IN, Yuan CC, Smith BR. Keenan RM, et al. Among authors: reader va. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3165-70. doi: 10.1016/s0960-894x(98)00555-1. Bioorg Med Chem Lett. 1998. PMID: 9873696
Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics.
Joberty G, Boesche M, Brown JA, Eberhard D, Garton NS, Humphreys PG, Mathieson T, Muelbaier M, Ramsden NG, Reader V, Rueger A, Sheppard RJ, Westaway SM, Bantscheff M, Lee K, Wilson DM, Prinjha RK, Drewes G. Joberty G, et al. Among authors: reader v. ACS Chem Biol. 2016 Jul 15;11(7):2002-10. doi: 10.1021/acschembio.6b00080. Epub 2016 May 19. ACS Chem Biol. 2016. PMID: 27197014
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.
Bantscheff M, Hopf C, Savitski MM, Dittmann A, Grandi P, Michon AM, Schlegl J, Abraham Y, Becher I, Bergamini G, Boesche M, Delling M, Dümpelfeld B, Eberhard D, Huthmacher C, Mathieson T, Poeckel D, Reader V, Strunk K, Sweetman G, Kruse U, Neubauer G, Ramsden NG, Drewes G. Bantscheff M, et al. Among authors: reader v. Nat Biotechnol. 2011 Mar;29(3):255-65. doi: 10.1038/nbt.1759. Epub 2011 Jan 23. Nat Biotechnol. 2011. PMID: 21258344
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors.
Bantscheff M, Eberhard D, Abraham Y, Bastuck S, Boesche M, Hobson S, Mathieson T, Perrin J, Raida M, Rau C, Reader V, Sweetman G, Bauer A, Bouwmeester T, Hopf C, Kruse U, Neubauer G, Ramsden N, Rick J, Kuster B, Drewes G. Bantscheff M, et al. Among authors: reader v. Nat Biotechnol. 2007 Sep;25(9):1035-44. doi: 10.1038/nbt1328. Epub 2007 Aug 26. Nat Biotechnol. 2007. PMID: 17721511
Vitamin B(4).
Barnes H, O'brien JR, Reader V. Barnes H, et al. Among authors: reader v. Biochem J. 1932;26(6):2035-40. doi: 10.1042/bj0262035. Biochem J. 1932. PMID: 16745034 Free PMC article. No abstract available.
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