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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, Latz E. Duewell P, et al. Among authors: rayner kj. Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938. Nature. 2010. PMID: 20428172 Free PMC article.
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Sheedy FJ, Grebe A, Rayner KJ, Kalantari P, Ramkhelawon B, Carpenter SB, Becker CE, Ediriweera HN, Mullick AE, Golenbock DT, Stuart LM, Latz E, Fitzgerald KA, Moore KJ. Sheedy FJ, et al. Among authors: rayner kj. Nat Immunol. 2013 Aug;14(8):812-20. doi: 10.1038/ni.2639. Epub 2013 Jun 30. Nat Immunol. 2013. PMID: 23812099 Free PMC article.
Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism.
Ouimet M, Koster S, Sakowski E, Ramkhelawon B, van Solingen C, Oldebeken S, Karunakaran D, Portal-Celhay C, Sheedy FJ, Ray TD, Cecchini K, Zamore PD, Rayner KJ, Marcel YL, Philips JA, Moore KJ. Ouimet M, et al. Among authors: rayner kj. Nat Immunol. 2016 Jun;17(6):677-86. doi: 10.1038/ni.3434. Epub 2016 Apr 18. Nat Immunol. 2016. PMID: 27089382 Free PMC article.
MicroRNAs regulating lipid metabolism in atherogenesis.
Rayner KJ, Fernandez-Hernando C, Moore KJ. Rayner KJ, et al. Thromb Haemost. 2012 Apr;107(4):642-7. doi: 10.1160/TH11-10-0694. Epub 2012 Jan 25. Thromb Haemost. 2012. PMID: 22274626 Free PMC article. Review.
microRNAs and cholesterol metabolism.
Moore KJ, Rayner KJ, Suárez Y, Fernández-Hernando C. Moore KJ, et al. Among authors: rayner kj. Trends Endocrinol Metab. 2010 Dec;21(12):699-706. doi: 10.1016/j.tem.2010.08.008. Epub 2010 Sep 27. Trends Endocrinol Metab. 2010. PMID: 20880716 Free PMC article. Review.
97 results